E0643
Erythropoietin Soluble Receptor human
>90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder
Synonym(s):
EPO sR
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About This Item
Recommended Products
biological source
human
Quality Level
recombinant
expressed in NSO cells
Assay
>90% (SDS-PAGE)
form
lyophilized powder
potency
74 ng/mL
mol wt
~25 kDa
packaging
pkg of 50 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... EPOR(2057)
Biochem/physiol Actions
Recombinant human soluble erythropoietin receptor binds erthropoietin with high affinity and is an erythropoietin antagonist.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose and 50 ug of bovine serum albumin per 1 ug of cytokine.
Analysis Note
The biological activity is measured by its ability to inhibit the recombinant human erythropoietin mediated cell proliferation of human TF1 cells.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Soluble Erythropoietin Receptor Contributes To Erythropoietin Resistance In End-stage Renal Disease.
Khankin, E.V., et al.
PLoS Biology, 5, e9246-e9246 (2010)
T Kitamura et al.
Journal of cellular physiology, 140(2), 323-334 (1989-08-01)
We have established a novel cell line, designated as TF-1, from a patient with erythroleukemia, which showed complete growth dependency on granulocyte-macrophage colony-stimulating factor (GM-CSF) or on interleukin-3 (IL-3) and carried a homogeneous chromosomal abnormality (54X). Erythropoietin (EPO) also sustained
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