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Safety Information

CLS354250

Corning® PuraMatrix(TM) Peptide Hydrogel

pack of 5 mL

Synonym(s):

lab equipment accessory

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About This Item

UNSPSC Code:
41116155
NACRES:
NA.7

packaging

pack of 5 mL

manufacturer/tradename

Corning 354250

Related Categories

General description

Corning PuraMatrix Peptide Hydrogel is a synthetic matrix used to create defined three dimensional (3D) micro-environments for a variety of cell culture experiments. To achieve optimal cell growth and differentiation, it is necessary to determine the appropriate mixture of this material and bioactive molecules (e.g., growth factors, extracellular matrix (ECM) proteins, and/or other molecules). Corning PuraMatrix Peptide Hydrogel consists of standard amino acids (1% w/v) and 99% water. Under physiological conditions, the peptide component self-assembles into a 3D hydrogel with a nanometer-scale fibrous structure. The hydrogel is readily formed in a Falcon culture dish, plate, or cell culture insert.
Corning PuraMatrix Peptide Hydrogel has been shown to promote differentiation of hepatocyte progenitor cells, rat pheochromocytoma cells (PC12), hippocampal neurons, and endothelial cells. Studies have also demonstrated the hydrogel supports the attachment of a variety of primary (e.g., neuronal, fibroblast, keratinocyte) and transformed (e.g., MG-63, SH-SY5Y, HEK293, NIH3T3) cell types. Other potential applications include stem cell proliferation, tumor cell migration and invasion, angiogenesis assays, and in vivo analyses of tissue regeneration.

Technical Specifications
  • 1% solution (w/v) of purified synthetic peptide
  • Packaged material exhibits pH of 2 to 4
  • Transparent
  • Devoid of animal-derived material and pathogens

Quality
  • Tested and found negative for bacteria, fungi, and mycoplasma
  • Cell viability = 80% based on cytotoxicity analysis of NIH3T3 fibroblasts
  • Identity confirmed using mass spectrometry
  • Demonstration of fiber formation using a self-assembly assay

Legal Information

Corning is a registered trademark of Corning, Inc.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

CLS354250-1EA:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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