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C8355

Sigma-Aldrich

D-erythro-Ceramide C8 1-phosphate

≥93% (HPLC), powder or solid

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About This Item

Empirical Formula (Hill Notation):
C26H52NO6P
Molecular Weight:
505.67
MDL number:
MFCD00270917
UNSPSC Code:
12352211
PubChem Substance ID:
329775167
NACRES:
NA.77

Quality Level

200

Assay

≥93% (HPLC)

form

film
powder or solid

color

white to off-white

solubility

DMSO: 15 mg/mL
ethanol: 20 mg/mL, clear to hazy (Colorless to faint yellow)

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](COP(O)(O)=O)NC(=O)CCCCCCC

InChI

1S/C26H52NO6P/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(28)24(23-33-34(30,31)32)27-26(29)22-20-17-8-6-4-2/h19,21,24-25,28H,3-18,20,22-23H2,1-2H3,(H,27,29)(H2,30,31,32)/b21-19+/t24-,25+/m0/s1

InChI key

VSSNYUXSRXINIP-WRBRXSDHSA-N

Biochem/physiol Actions

Cell permeable stimulator of DNA synthesis in cultured fibroblasts; antagonizes mitogenic activity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

C8355-BULK:
C8355-1MG-PW:
C8355-VAR:
C8355-1MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sigma-Aldrich

S9666

Sphingosine 1-phosphate

A Gomez-Muñoz et al.
Molecular pharmacology, 47(5), 833-839 (1995-05-01)
Ceramide and ceramide-1-phosphate are sphingolipid analogues of diacylglycerol and phosphatidate, respectively, and they are putative second messengers of agonist-stimulated sphingomyelin metabolism. The interactions of exogenous cell-permeable ceramides and ceramide-1-phosphates in modifying DNA synthesis and signal transduction were investigated in Rat-1

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