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Safety Information

C7438

Sigma-Aldrich

Chaperonin 10 from Escherichia coli

≥95.0% (SDS-PAGE), recombinant, expressed in E. coli overproducing strain, lyophilized powder

Synonym(s):

GroES

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About This Item

MDL number:
MFCD00163256
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

Escherichia coli

Quality Level

200

recombinant

expressed in E. coli overproducing strain

Assay

≥95.0% (SDS-PAGE)

form

lyophilized powder

technique(s)

activity assay: suitable

UniProt accession no.

P61604

storage temp.

2-8°C

Gene Information

human ... HSPE1(3336)

Biochem/physiol Actions

Chaperonin60 (GroEL) and chaperonin10 (GroES) belong to the ubiquitous family of heat-shock molecular chaperones found in prokaryotes and in eukaryotic organelles. The chaperonins assist the folding of nascent, organelle-imported or stress-destabilized polypeptides. In vitro, purified GroEL together with purified GroES in the presence of Mg-ATP facilitate refolding and reactivation of denatured proteins, e.g., the photosynthetic enzyme rubisco and the mitochondrial enzyme rhodanese.
The folding activity of a 1:1 molar mixture of GroEL and GroES was tested using urea-denatured rhodanese. At least 2-fold reactivation of rhodanese over the spontaneous reactivation was obtained.

Packaging

Package size based on protein content.

Physical form

Lyophilized powder containing Tris buffer salts, potassium chloride, dithiothreitol and trehalose as stabilizer.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

C7438-VAR:
C7438-BULK:
C7438-250UG-PW:
C7438-250UG:

Certificates of Analysis (COA)

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