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Safety Information

C6534

Sigma-Aldrich

Anti-Chicken Egg Albumin antibody produced in rabbit

whole antiserum

Synonym(s):

Anti-Albumin, chicken egg

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About This Item

MDL number:
MFCD00162221
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

species reactivity

chicken

technique(s)

indirect ELISA: 1:80,000
quantitative precipitin assay: 3-5 mg/mL

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

chicken ... Alb(396197)

General description

Chicken/hen′s egg albumin, also known as ovalbumin (OVA), is the most abundant egg white protein. It is surrounded by B-cell epitopes, which are bound by specific IgE antibodies. In addition, it also contains CD4+ T cell epitopes. Ovalbumin is a monomeric protein with a molecular mass of 45000 Da.

Application

Anti-Chicken Egg Albumin antibody produced in rabbit has been used in:
  • quantitative precipitin assay
  • indirect enzyme linked immunoassay (ELISA)
  • development of nonimmune rabbit antiserum against chicken ovalbumin

Biochem/physiol Actions

Chicken/hen′s egg albumin or ovalbumin (OVA) is a major allergen found in egg white and is widely used in allergy research. It has been widely used to determine the characteristics of class II major histocompatibility complex (MHC)-peptide binding and T-cell activation.

Preparation Note

treated to remove lipoproteins

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

C6534-VAR:
C6534-2ML:
C6534-BULK:

Certificates of Analysis (COA)

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Professional phagocytes internalize self and non-self particles by phagocytosis to initiate innate immune responses. After internalization, the formed phagosome matures through fusion and fission events with endosomes and lysosomes to obtain a more acidic, oxidative and hydrolytic environment for the
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Journal of immunology (Baltimore, Md. : 1950), 192(5), 2252-2260 (2014-02-04)
Therapeutic Abs possess several clinically relevant mechanisms of action including perturbation of tumor cell signaling, activation of complement-dependent cytotoxicity, Ab-dependent cellular cytotoxicity (ADCC), Ab-dependent cellular phagocytosis (ADCP), and induction of adaptive immunity. In view of the important role of phagocytic
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