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Key Documents

Safety Information

C0755

Sigma-Aldrich

Conalbumin from chicken egg white

Substantially iron-free

Synonym(s):

Ovotransferrin

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About This Item

CAS Number:
1391-06-6
EC Number:
215-727-0
MDL number:
MFCD00130856
UNSPSC Code:
12352202
NACRES:
NA.25

biological source

chicken egg white

Assay

≥98% (agarose gel electrophoresis)

form

powder

UniProt accession no.

P02789

storage temp.

−20°C

Gene Information

chicken ... TF(396241)

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General description

Conalbumin is an iron-binding protein. It is mainly present in the egg white of hen. It is also termed as ovotransferrin. It is a member of the transferrin iron-binding glycoproteins family. Ovotransferrin is also known an an acute?phase protein (APP)in some organisms. It is the second main protein found in egg white.

Application

Conalbumin from chicken egg white has been used:
  • as ovotransferrin standard in 96?well microplate assay to investigate on ovotransferrin-like activity in the plasma of wild birds
  • to examine its effects on osteoclastogenesis
  • to study its partitioning in aqueous two-phase systems

Biochem/physiol Actions

Conalbumin/ovotransferrin plays a key role in avian natural immunity. It has the ability to prevent bacterial growth and possesses immunomodulatory functions. Ovotransferrin also exhibits antimicrobial and antioxidant activities.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H317,H334

Precautionary Statements

P261 - P280 - P342 + P311

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

C0755-1G:
C0755-500MG:
C0755-5G:
C0755-VAR:
C0755-100MG:
C0755PROC:
C0755-BULK:
C0755-CP:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A simple assay for measurement of ovotransferrin-a marker of inflammation and infection in birds
Horrocks NPC, et al.
Methods in Ecology and Evolution, 2(5), 518-526 (2011)
Siderophores and transferrins
Dertz EA and Raymond KN
ChemInform, 35(49), no-no (2004)
Bacterial iron metabolism in infection and immunity
Microbial iron metabolism, 517-551 (1974)
Physiological roles of ovotransferrin
Giansanti F, et al.
Biochimica et biophysica acta. General subjects, 1820(3), 218-225 (2012)
Egg White Ovotransferrin Attenuates RANKL-Induced Osteoclastogenesis and Bone Resorption
Shang N and Wu J
Nutrients, 11(9), 2254-2254 (2019)
View All Related Papers

Articles

HPLC Analysis of Protein Standards (1) on BIOshell™ A400 Protein C4

For use as a marker in SDS-PAGE; Albumin from chicken egg white, For use as a marker in SDS-PAGE; L-Lactic Dehydrogenase from rabbit muscle, Type XI, lyophilized powder, 600-1,200 units/mg protein

Chromatograms

application for HPLC

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