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Safety Information

A9887

Sigma-Aldrich

Aflatoxin B2

≥98% (HPLC), powder, mycotoxin

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About This Item

Empirical Formula (Hill Notation):
C17H14O6
CAS Number:
Molecular Weight:
314.29
Beilstein:
1355115
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

product name

Aflatoxin B2,

form

powder

Quality Level

storage temp.

2-8°C

SMILES string

COc1cc2O[C@H]3OCC[C@H]3c2c4OC(=O)C5=C(CCC5=O)c14

InChI

1S/C17H14O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h6,8,17H,2-5H2,1H3/t8-,17+/m0/s1

InChI key

WWSYXEZEXMQWHT-WNWIJWBNSA-N

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General description

Aflatoxin B2/AFB2 is a toxic mycotoxin.

Application

Aflatoxin B2 has been used as a standard in a study to find out aflatoxins in various foods, spices and feedstuffs by high performance liquid chromatography (HPLC). It has also been used as a standard to determine aflatoxins in honey by HPLC.

Biochem/physiol Actions

Aflatoxin B2 is a hepatocarcinogen. Food contaminant produced by Aspergillus flavus, a common soil fungus. Aflatoxin B2/AFB2 may have dangerous hepatotoxic, teratogenic and carcinogenic actions on various forms of livestock.

Warning

Possibly carcinogenic.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 1B - Muta. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

A9887-1MG-KC:
A9887-5MG-PW:
A9887-VAR:
A9887-1MG:
A9887-10MG-KC:
A9887-1MG-PW:
A9887-5MG:
A9887-BULK:
A9887-10MG:
A9887-10MG-PW:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Induction of mitochondria-mediated apoptosis and PI3K/Akt/mTOR-mediated autophagy by aflatoxin B2 in hepatocytes of broilers
Chen B, et al.
Oncotarget, 7(51), 84989-84989 (2016)
A STUDY ON AFLATOXINS IN VARIOUS FOODS, SPICES AND FEEDSTUFFS BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
OZ, T. Y. V.
The ISME Journal, 31, 11-16 (2016)
Bacillaceae spores, fungi and aflatoxins determination in honey Esporos de Bacillaceae, fungos e aflatoxinas em mel
Martins H M, et al.
RN (2003)
Zarrin Es'haghi et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(28), 3034-3040 (2011-09-20)
The new pre-concentration technique, hollow fiber-solid phase microextraction based on carbon nanotube reinforced sol-gel and liquid chromatography-photodiode array detection was applied to determination of aflatoxins B(1), B(2) (AFB(1), AFB(2)) in rice, peanut and wheat samples. This research provides an overview
D Tang et al.
Biosensors & bioelectronics, 25(2), 514-518 (2009-08-25)
A novel membrane-based lateral-flow immunodipstick assay was developed for the fast screening of aflatoxin B(2) (AFB(2)) as a model compound in food samples. The detector reagent consisted of magnetic nanogold microspheres (MnGMs) with nano-Fe(2)O(3) particles as core and gold nanoparticles

Articles

Carcinogenesis and Epigenetics

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