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A8597

Sigma-Aldrich

1-Amino-3,3-diethoxypropane

liquid, ≥97%

Synonym(s):

3-Aminopropionaldehyde diethylacetal

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About This Item

Empirical Formula (Hill Notation):
C7H17NO2
CAS Number:
41365-75-7
Molecular Weight:
147.22
MDL number:
MFCD00142581
UNSPSC Code:
12352202
PubChem Substance ID:
24891347
NACRES:
NA.77

Product Name

1-Amino-3,3-diethoxypropane, ≥97%, liquid

biological source

synthetic (organic)

Quality Level

100

Assay

≥97%

form

liquid

solubility

water: miscible

density

0.91 g/mL at 25 °C (lit.)

storage temp.

room temp

SMILES string

CCOC(CCN)OCC

InChI

1S/C7H17NO2/c1-3-9-7(5-6-8)10-4-2/h7H,3-6,8H2,1-2H3

InChI key

PXXMSHBZYAOHBD-UHFFFAOYSA-N

General description

1-Amino-3,3-diethoxypropane is an effective modulator of alginate and chitosan based hydrogels and effectively used for the delivery of bone marrow stromal cells (BMSCs) for regeneration of cartilage.

Application

1-Amino-3,3-diethoxypropane has been used:
  • with alginate in the preparation of hydrogel
  • in the generation of polyethylene glycol (PEG) polyethylenimine (PEI) polyplexes conjugate for transfection studies in hepatocellular carcinoma cell cultures
  • as a component of pH-sensitive PEG derivative for lipopolyplexes formation

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

172.4 °F - closed cup

Flash Point(C)

78 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 3 petroleums
Hazardous rank III
Water insoluble liquid

JAN Code

A8597-BULK:
A8597-VAR:
A8597-25G:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ7403
MKCM7340
MKCM7181
MKCM4820
MKCJ4803

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Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding
Fella C, et al.
European Journal of Pharmaceutical Sciences, 34(4-5), 309-320 (2008)
BMSCs laden injectable amino-diethoxypropane modified alginate-chitosan hydrogel for hyaline cartilage reconstruction
Wan W, et al.
Journal of Material Chemistry B: Materials for Biology and Medicine, 3(9), 1990-2005 (2015)
Pyridylhydrazone-based PEGylation for pH-reversible lipopolyplex shielding
Nie Y, et al.
Biomaterials, 32(3), 858-869 (2011)
Caroline R Basso et al.
Talanta, 197, 482-490 (2019-02-18)
A new immunosensor using hybrid nanomaterials for the detection of dengue virus was demonstrated in this work. This immunosensor composed of nanoparticles of γ-Fe2O3(SAMN) modified with MPA- SAMN@MPA was characterized by FTIR spectroscopy, transmission electron microscopy,quartz crystal microbalance, UV-vis and
Massimiliano Magro et al.
Amino acids, 51(4), 679-690 (2019-02-07)
The preservation of enzymatic activity is a fundamental requirement for exploiting hybrid nano-bio-conjugates, and the control over protein-nanoparticle interactions, leading to stable and catalytically active hybrids, represents the key for designing new biosensing platforms. In this scenario, surface active maghemite

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