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Safety Information

A8511

Sigma-Aldrich

Luminol

≥97% (HPLC)

Synonym(s):

3-Aminophthalhydrazide, 5-Amino-2,3-dihydro-1,4-phthalazinedione

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About This Item

Empirical Formula (Hill Notation):
C8H7N3O2
CAS Number:
521-31-3
Molecular Weight:
177.16
Beilstein:
383929
EC Number:
208-309-4
MDL number:
MFCD00006890
UNSPSC Code:
12352204
PubChem Substance ID:
24891343
NACRES:
NA.83

Quality Level

200

Assay

≥97% (HPLC)

form

powder or chunks

mp

>300 °C (lit.)

solubility

DMSO: 50 mg/mL, clear to slightly hazy

SMILES string

Nc1cccc2C(=O)NNC(=O)c12

InChI

1S/C8H7N3O2/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12/h1-3H,9H2,(H,10,12)(H,11,13)

InChI key

HWYHZTIRURJOHG-UHFFFAOYSA-N

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General description

Luminol is a chemiluminescent compound, which belongs to the class of cyclic acyl hydrazides. It exhibits chemiluminescence, when oxidized by oxidizing agents. Luminol may be associated with nausea, vomiting and mucosa irritation in eyes and skin.

Application

Luminol has been used in chemiluminescence assay.

Features and Benefits

Used for chemiluminescence analysis of, for example, metal cations, blood, and glucococorticoids.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

A8511-1G:
A8511-BULK:
A8511-25G:
A8511-VAR:
A8511-5G:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ8893
MKCP9100
MKCN3605
MKCL1884
MKCH3268

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Reference values of reactive oxygen species in seminal ejaculates using chemiluminescence assay
Agarwal A, et al.
Journal of Assisted Reproduction and Genetics, 32(12), 1721-1729 (2015)
Luminol-based chemiluminescent signals: clinical and non-clinical application and future uses
Khan P, et al.
Applied Biochemistry and Biotechnology, 173(2), 333-355 (2014)
Christophe A Marquette et al.
Analytical and bioanalytical chemistry, 385(3), 546-554 (2006-05-23)
This critical review discusses the results published between 2000 and 2005 on the development of analytical systems based on the luminol chemiluminescent and electrochemiluminescent reactions. An increasing number of non-specific detection systems based on the enhancing, inhibiting or catalysing effect
Fuan Wang et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(50), 16030-16036 (2012-10-20)
The Cu(2+)-dependent ligation DNAzyme is implemented as a biocatalyst for the colorimetric or chemiluminescence detection of Cu(2+) ions, Hg(2+) ions, or cocaine. These sensing platforms are based on the structural tailoring of the sequence of the Cu(2+)-dependent ligation DNAzyme for
Feng-Ming Hsu et al.
Scientific reports, 5, 10291-10291 (2015-05-20)
Esophageal cancer patients with pathological complete response (pCR) to neoadjuvant chemoradiation (CRT) have favorable outcomes. Currently, there was no reliable biomarker predicting the response to CRT. Perioperative circulating mRNA may be associated with prognosis, but its application for predicting treatment
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