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Safety Information

A6553

Sigma-Aldrich

DL-2-Amino-5-phosphonovaleric acid lithium salt

~95%

Synonym(s):

DL-2-Amino-5-phosphonopentanoic acid, AP-5

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About This Item

Linear Formula:
C5H11NO5PLi
CAS Number:
125229-62-1
Molecular Weight:
203.06
MDL number:
MFCD00078901
UNSPSC Code:
12352106
PubChem Substance ID:
24891104
NACRES:
NA.26

Assay

~95%

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

SMILES string

[Li].NC(CCCP(O)(O)=O)C(O)=O

InChI

1S/C5H12NO5P.Li.H/c6-4(5(7)8)2-1-3-12(9,10)11;;/h4H,1-3,6H2,(H,7,8)(H2,9,10,11);;

InChI key

QIVHTKSFMZBERS-UHFFFAOYSA-N

Gene Information

rat ... Grik1(29559) , Grin2a(24409) , Grin2b(24410)

Related Categories

Biochem/physiol Actions

DL-2-Amino-5-phosphonovaleric acid is a selective N-methyl-d-aspartate (NMDA) receptor antagonist used frequently in studies of neurological processes
Anticonvulsant; potent and selective antagonist for NMDA receptors.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

A6553-BULK:
A6553-VAR:
A6553-10MG:
A6553-25MG:
A6553-50MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Journal of neurophysiology, 107(3), 902-912 (2011-11-25)
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A Osorio-Espinoza et al.
Neuroscience, 176, 20-31 (2011-01-05)
The globus pallidus, a neuronal nucleus involved in the control of motor behavior, expresses high levels of histamine H(3) receptors (H(3)Rs) most likely located on the synaptic afferents to the nucleus. In this work we studied the effect of the
Jessica M André et al.
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NMDA glutamate receptors (NMDARs) and nicotinic acetylcholine receptors (nAChRs) are both involved in learning and synaptic plasticity. Increasing evidence suggests processes mediated by these receptors may interact to modulate learning; however, little is known about the neural substrates involved in
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Journal of neurophysiology, 112(4), 890-902 (2014-05-23)
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