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Safety Information

A1900

Sigma-Aldrich

Albumin, Monomer bovine

Monomer ≥97 %

Synonym(s):

Albumin powder, Bovine albumins

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About This Item

CAS Number:
9048-46-8
EC Number:
232-936-2
MDL number:
MFCD00130384
UNSPSC Code:
12352202
eCl@ss:
42010201
NACRES:
NA.26

biological source

bovine

Assay

≥97% (PAGE)

form

lyophilized powder

composition

Monomer, ≥97%

solubility

H2O: soluble 50 mg/mL

UniProt accession no.

P02769

storage temp.

2-8°C

Gene Information

bovine ... ALB(280717)

General description

The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein can bind to ligands.

Application

Albumin, Monomer bovine has been used as a:
  • molecular weight (MW) and polydispersion index (PDI) reference standard for the analysis of hyaluronic acid (HA)-based eye drops
  • standard in multi-angle light scattering coupled with size exclusion chromatography (SEC-MALS) for calibration
  • model protein to generate subvisible particles (SVPs) for flow imaging microscopy studies

The binding properties of albumin can be used for a wide range of clinical, pharmaceutical, and biochemical applications.

Biochem/physiol Actions

Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals.

Preparation Note

Isolated from albumin (A4503) as described for mercaptalbumin in Janatova, J., et al., J. Biol. Chem., 243, 3612 (1968).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

A1900-500MG:
A1900-BULK:
A1900-1G:
A1900-VAR:
A1900-20ML:
A1900-250MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Pasquale Aragona et al.
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To assess the physicochemical properties of hyaluronic acid (HA)-based artificial tears. The average molecular weight (MW) and polydispersion index (PDI) of HA in 18 commercially available artificial tears were determined by light scattering/high-performance liquid chromatography. Osmolality, pH, viscosity, and sodium
Surendra Dasari et al.
Journal of proteome research, 8(3), 1263-1270 (2009-01-29)
A robust peptide quantification method was developed where overlapping peptide isotopic distributions were fit with predicted peptide isotopic envelope mixture models (IEMMs). Application to two difficult quantitative problems was demonstrated. The first was the quantification of deamidation, where masses of
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Secondary structural change of bovine serum albumin in thermal denaturation up to 130 degrees C and protective effect of sodium dodecyl sulfate on the change.
Moriyama, Y., et al.
The Journal of Physical Chemistry B, 112, 16585-16589 (2008)
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