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Safety Information

01640

Sigma-Aldrich

Acridine

BioReagent, suitable for fluorescence, ≥97.0% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C13H9N
CAS Number:
260-94-6
Molecular Weight:
179.22
Beilstein:
120200
EC Number:
205-971-6
MDL number:
MFCD00005025
UNSPSC Code:
12171500
eCl@ss:
39210107
PubChem Substance ID:
329747337
NACRES:
NA.32

product line

BioReagent

Quality Level

100

Assay

≥97.0% (HPLC)

bp

346 °C (lit.)

mp

106-111 °C
107-110 °C (lit.)

solubility

ethanol: 0.5 g/10 mL, clear (hot)
carbon disulfide: soluble
diethyl ether: soluble
ethanol: soluble
hydrocarbons: soluble

fluorescence

λex 360 nm; λem 417 nm in ethanol

suitability

suitable for fluorescence

SMILES string

c1ccc2nc3ccccc3cc2c1

InChI

1S/C13H9N/c1-3-7-12-10(5-1)9-11-6-2-4-8-13(11)14-12/h1-9H

InChI key

DZBUGLKDJFMEHC-UHFFFAOYSA-N

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Application

The fluorescence intensity, fluorescence quantum yield, time of decay, and lifetime are dependent upon the solvent. For example, the fluorescence intensity varies from being moderately strong in aqueous solution and very weak in hydrocarbon solvents. Additionally, the quantum yield has been demonstrated to increase with decreasing temperatures, for all solvent conditions.

Analysis Note

In addition to the emission maximum at 417 nm, there are lower maxima at 435, 400 and 460 nm.

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

01640-VAR:
01640-50G:
01640-10G:
01640-BULK:
01640-1G:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Subnanosecond Time-Resolved Fluorescence of Acridine in Solution
Diverdi, L. A., and Topp, M. R.
The Journal of Physical Chemistry, 88, 3447-3447 (1984)
J S Plested et al.
Infection and immunity, 69(5), 3203-3213 (2001-04-09)
A recently described flow cytometric opsonophagocytic assay (OPA) was adapted to quantify the functional activity of serum antibodies specifically directed against serogroup B inner core lipopolysaccharide (LPS) of Neisseria meningitidis. The percentage of human peripheral polymorphonuclear leukocytes and monocytes (PMNms)
Ulrike K Buchwald et al.
PloS one, 9(12), e116268-e116268 (2014-12-31)
The identification of Mycobacterium-tuberculosis (Mtb) infected individuals remains a challenge due to an insufficient understanding of immune responses detected with the current diagnostic tests for latent tuberculosis i.e. the tuberculin skin test (TST) or IFN-γ release assays (IGRAs) and an
Kevin Tartour et al.
PLoS pathogens, 13(9), e1006610-e1006610 (2017-09-29)
IFITMs are broad antiviral factors that block incoming virions in endosomal vesicles, protecting target cells from infection. In the case of HIV-1, we and others reported the existence of an additional antiviral mechanism through which IFITMs lead to the production
Edward Greenfield et al.
eLife, 3 (2014-12-11)
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012. This Registered Report describes the proposed replication plan
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