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217638

Sigma-Aldrich

Sodium iodide

ReagentPlus®, ≥99%

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About This Item

Linear Formula:
NaI
CAS Number:
7681-82-5
Molecular Weight:
149.89
EC Number:
231-679-3
MDL number:
MFCD00003532
UNSPSC Code:
12352302
PubChem Substance ID:
329752204
NACRES:
NA.21
Assay:
≥99%
form:
powder
solubility:
water: soluble(lit.)

vapor density

>1 (vs air)

Quality Level

100

product line

ReagentPlus®

Assay

≥99%

form

powder

impurities

<1.0% water

pH

6-9 (20 °C, 50 g/L)

mp

661 °C (lit.)

solubility

water: soluble(lit.)

SMILES string

[Na+].[I-]

InChI

1S/HI.Na/h1H;/q;+1/p-1

InChI key

FVAUCKIRQBBSSJ-UHFFFAOYSA-M

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General description

Sodium iodide is an ionic compound that can be prepared by treating sodium hydroxide or sodium carbonate with hydriodic acid. It is a versatile reagent used as an iodide source in organic synthesis.

Application

Sodium iodide can be used as a catalyst :
  • To synthesize α-alkoxylated ketones.
  • For N-tert-butoxy carbonylation of amines.
It can also be used as a reagent for the conversion of aryl amines to aryl iodides.

Other Notes

Go to Redi-Dri™ Product Listing 793558

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

217638-VAR-D:
217638-BULK:
217638-100G:4548173986586
217638-5G:4548173986593
217638-2.5KG:4548173986562
217638-500G:4548173986579
217638-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ4370
MKCQ2794
MKCQ1876
MKCP6433
MKCP6432

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Eagleson M.
Concise Encyclopedia Chemistry, 648-648 (1994)
Synthetic methods and reactions. 62. Transformations with chlorotrimethylsilane/sodium iodide, a convenient in situ iodotrimethylsilane reagent.
Olah GA, et al.
The Journal of Organic Chemistry, 44(8), 1247-1251 (1979)
The Chesapeake Bay Institute technique for the Winkler dissolved oxygen method.
Carpenter JH.
Limnology and Oceanography, 10(1), 141-143 (1965)
Eagleson M.
Concise Encyclopedia Chemistry, 999-999 (1994)
Caroline Serrano-Nascimento et al.
Molecular and cellular endocrinology, 349(2), 154-161 (2011-10-18)
Iodide excess acutely downregulates NIS mRNA expression, as already demonstrated. PCCl3 cells treated or not with NaI, NaI+NaClO(4) or NaI+Methimazole, for 30 min to 24 h, were used to further explore how iodide reduces NIS gene expression. NIS mRNA expression
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