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Safety Information

F0763

Sigma-Aldrich

Fura 2 pentapotassium salt

≥80% purity, powder

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About This Item

Empirical Formula (Hill Notation):
C29H22K5N3O14
CAS Number:
Molecular Weight:
831.99
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

Fura 2 pentapotassium salt, ≥80%

Quality Level

Assay

≥80%

form

powder

color

yellow

solubility

1 M NaOH: 10 mg/mL

εmax

24-37 at 363 nm (pH 7.2)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

[K+].[K+].[K+].[K+].[K+].Cc1ccc(N(CC([O-])=O)CC([O-])=O)c(OCCOc2cc3cc(oc3cc2N(CC([O-])=O)CC([O-])=O)-c4ncc(o4)C([O-])=O)c1

InChI

1S/C29H27N3O14.5K/c1-15-2-3-17(31(11-24(33)34)12-25(35)36)20(6-15)43-4-5-44-21-7-16-8-22(28-30-10-23(46-28)29(41)42)45-19(16)9-18(21)32(13-26(37)38)14-27(39)40;;;;;/h2-3,6-10H,4-5,11-14H2,1H3,(H,33,34)(H,35,36)(H,37,38)(H,39,40)(H,41,42);;;;;/q;5*+1/p-5

InChI key

HQKWBBCTCLUGSX-UHFFFAOYSA-I

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General description

Fura 2 pentapotassium salt (fura-2) is a fluorescent ratiometric Ca2+ dye. Fura 2 pentapotassium salt (fura-2) helps to estimate the level of cytosolic Ca(2+) by determining the emission found at 510 nm after alternating excitation at 340 nm and 380 nm (F340/F380 ratio). Hence, it is considered as the standard for quantitative intracellular calcium measurements.

Application

Cell impermeable fluorescent probe for Ca2+.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

F0763-BULK:
F0763-1MG-PW:
F0763-.1MG:
F0763-VAR:
F0763-.5MG:
F0763-1MG:


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Resveratrol interferes with fura-2 intracellular calcium measurements
Kopp, et al.
Journal of Fluorescence, 24(2), 279-284 (2014)
Ram Chandra Paudel et al.
Biochemical and biophysical research communications, 450(4), 1626-1630 (2014-07-19)
Fura-2 is a commonly used fluorescent Ca(2+) dye that allows an accurate determination of cytosolic Ca(2+) levels by measuring the emission obtained at 510 nm after alternating excitation at 340 nm and 380 nm (F340/F380 ratio). Previous studies, based on

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