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Safety Information

D9257

Supelco

Dihydrotachysterol

analytical standard

Synonym(s):

9,10-Secoergosta-5,7,22-trien-3β-ol, DHT2

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About This Item

Empirical Formula (Hill Notation):
C28H46O
CAS Number:
67-96-9
Molecular Weight:
398.66
EC Number:
200-672-7
UNSPSC Code:
41116107
PubChem Substance ID:
24894275
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥98%

form

solid

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

C[C@@H]([C@@]1([H])CC[C@@]2([H])/C(CCC[C@@]21C)=C/C=C3[C@@H](C)CC[C@H](O)C/3)/C=C/[C@H](C)C(C)C

InChI

1S/C28H46O/c1-19(2)20(3)12-13-22(5)25-16-17-26-23(10-8-18-28(25,26)6)14-15-24-21(4)9-7-11-27(24)29/h12-15,19-22,25-27,29H,7-11,16-18H2,1-6H3/b13-12+,23-14+,24-15+/t20-,21-,22+,25?,26?,27-,28+/m0/s1

InChI key

DTSXXSAWQHPLEF-GFVAUXBKSA-N

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General description

Dihydrotachysterol is a vitamin D analog in the reduced form, which has implications in the studies of calcemic and cell differentiating action of the hormone, 1α,25-dihydroxyvitamin D3. It has been indicated as a medication for the treatment of hypoparathyroidism and renal osteodystrophy.

Application

Dihydrotachysterol may be used as an analytical reference standard for the determination of the analyte in biological samples by chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301,H413

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 4

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

D9257-1G:
D9257-VAR:
D9257-50MG:
D9257-BULK:
D9257-250MG:
D9257-10MG:

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Certificates of Analysis (COA)

Lot/Batch Number
WXBD4543V
WXBC9660V
WXBC6943V
067K1450V
067K1450

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Serum dihydrotachysterol levels and biological action in normal man
TAYLOR A, et al.
The Journal of clinical endocrinology and metabolism, 67(1), 198-202 (1988)
1, 25 (OH) 2D levels in dihydrotachysterol-treated patients: Influence on 1, 25 (OH) 2D assays
Taylor A and Norman ME
Journal of Bone and Mineral Research, 2(6), 567-570 (1987)
Gas chromatographic studies of vitamins D2 and D3
Nair PP, et al.
Analytical Chemistry, 37(6), 631-636 (1965)
Ali Mohammad Tohari et al.
Experimental cell research, 392(1), 112023-112023 (2020-04-24)
Diabetic retinopathy (DR) is a diabetes-associated complication characterized by irreversible deterioration of the microvessels within the retina, leading subsequently to severe retinal damage and vision loss. Vitamin D (VITD), a steroid hormone, plays multiple physiological functions in cellular homeostasis. Deficiency
G Heather Wilson et al.
Journal of the American Veterinary Medical Association, 222(8), 1093-1096 (2003-04-25)
A 1.5-year-old ferret examined because of seizures was found to have low serum calcium, high serum phosphorus, and extremely high serum parathyroid hormone concentrations. Common causes of these abnormalities, including nutritional secondary hyperparathyroidism, chronic renal secondary hyperparathyroidism, tumor lysis syndrome
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