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93285

Supelco

2,4,6-Tris(2-pyridyl)-s-triazine

for spectrophotometric det. of Fe, ≥99.0% (HPLC)

Synonym(s):

2,4,6-Tri(2-pyridyl)-s-triazine, TPTZ

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About This Item

Empirical Formula (Hill Notation):
C18H12N6
CAS Number:
Molecular Weight:
312.33
Beilstein:
282581
EC Number:
MDL number:
UNSPSC Code:
12000000
PubChem Substance ID:
NACRES:
NA.21

Quality Level

Assay

≥99.0% (HPLC)

form

lumps

quality

for spectrophotometric det. of Fe

technique(s)

UV/Vis spectroscopy: suitable

loss

≤0.1 wt. % loss on drying

mp

247-249 °C (lit.)
248-252 °C

solubility

methanol: 100 mg/mL, clear to slightly hazy

cation traces

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES string

c1ccc(nc1)-c2nc(nc(n2)-c3ccccn3)-c4ccccn4

InChI

1S/C18H12N6/c1-4-10-19-13(7-1)16-22-17(14-8-2-5-11-20-14)24-18(23-16)15-9-3-6-12-21-15/h1-12H

InChI key

KMVWNDHKTPHDMT-UHFFFAOYSA-N

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General description

2,4,6-Tris(2-pyridyl)-s-triazine is a Case and Koft compound generally used in determination of iron in a colorimetric analysis.

Application


  • Fe(II/III) and Mn(II) complexes based on 2,4,6-tris(2-pyridyl)-triazine: synthesis, structures, magnetic and biological properties.: This research explores the synthesis and structural characterization of iron and manganese complexes with 2,4,6-Tris(2-pyridyl)-s-triazine. The study highlights the compound′s role in forming complexes with unique magnetic and biological properties, making it suitable for applications in materials science and biochemistry (Baca et al., 2022).

  • Development of spray-dried N-acetylcysteine dry powder for inhalation.: The article discusses the formulation of a spray-dried powder using 2,4,6-Tris(2-pyridyl)-s-triazine to improve drug delivery in pulmonary systems. This technique enhances the stability and bioavailability of the drug, demonstrating the compound′s versatility in pharmaceutical applications (Ricci et al., 2023).

  • Determination of Antioxidant, Anti-Alzheimer, Antidiabetic, Antiglaucoma and Antimicrobial Effects of Zivzik Pomegranate (Punica granatum)-A Chemical Profiling by LC-MS/MS.: This study uses 2,4,6-Tris(2-pyridyl)-s-triazine in the chemical profiling of pomegranate extracts, assessing their potential in treating various diseases. The results underscore the compound′s role in enhancing LC-MS/MS analysis for detecting bioactive compounds in natural products (Gulcin et al., 2023).

  • Photoprotection and Antiaging Activity of Extracts from Honeybush (Cyclopia sp.)-In Vitro Wound Healing and Inhibition of the Skin Extracellular Matrix Enzymes: Tyrosinase, Collagenase, Elastase and Hyaluronidase.: In this research, 2,4,6-Tris(2-pyridyl)-s-triazine is used to study the effects of Honeybush extracts on skin health. The compound′s utility in dermatological research and its effectiveness in enhancing analytical methods for studying pharmacological activities are demonstrated (Ochocka et al., 2023).

  • Comprehensive Phytochemical Content by LC/MS/MS and Anticholinergic, Antiglaucoma, Antiepilepsy, and Antioxidant Activity of Apilarnil (Drone Larvae).: This paper discusses the use of 2,4,6-Tris(2-pyridyl)-s-triazine in the LC/MS/MS analysis of drone larvae extracts, evaluating their potential pharmacological activities. The study highlights the compound′s critical role in enhancing the sensitivity and specificity of mass spectrometric methods (Gülçin et al., 2023).

Other Notes

Reagent for the spectrophotometric determination of Fe(II) and of total Fe

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

93285-VAR:
93285-BULK:
93285-INTR:
93285-1G:
93285-5G:
93285-25G:


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P.F. Collins et al.
Analytical Chemistry, 31, 1862-1862 (1959)
J. Flock et al.
Fresenius Journal of Analytical Chemistry, 346, 667-667 (1993)
2, 4, 6-Tripyridyl-s-triazine as reagent for iron. Determination of iron in limestone, silicates, and refractories.
Collins, Peter F., Harvey Diehl, and G. Frederick Smith.
Analytical Chemistry, 31.11, 1862-1867 (1959)
Atomic-absorption spectrometric determination of copper(I) after adsorption of its 2,4,6-tri(2-pyridyl)-1,3,5-triazine complex with tetraphenylborate anion on microcrystalline naphthalene.
J L Lin et al.
The Analyst, 110(11), 1351-1354 (1985-11-01)
D Ben-Shachar et al.
Journal of neurochemistry, 45(4), 999-1005 (1985-10-01)
Nutritional iron deficiency induced in rats causes a selective reduction of [3H]spiperone binding in caudate nucleus. This effect can be reversed by iron supplementation in vivo. The possibility that iron may be involved in the dopamine D2 receptor was investigated

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