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Safety Information

89921

Supelco

(±)-2,4-Dihydroxybutyric acid lithium salt

≥95.0% (GC)

Synonym(s):

2,4-Dihydroxybutanoic acid lithium salt

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About This Item

Empirical Formula (Hill Notation):
C4H8O4
CAS Number:
1518-62-3
Molecular Weight:
120.10
UNSPSC Code:
12352106
PubChem Substance ID:
329769561
NACRES:
NA.24

Quality Level

100

Assay

≥95.0% (GC)

application(s)

clinical testing

format

neat

storage temp.

2-8°C

InChI

1S/C4H8O4/c5-2-1-3(6)4(7)8/h3,5-6H,1-2H2,(H,7,8)

InChI key

UFYGCFHQAXXBCF-UHFFFAOYSA-N

Related Categories

Biochem/physiol Actions

Various cases of succinic semialdehyde dehydrogenase deficiency have shown consistently increased amounts of this metabolite, while 2,4-dihydroxybutanoic acid is usually absent in normal human urine extracts or in only trace constituents in neonates.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

89921-10MG:
89921-BULK:
89921-50MG:
89921-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
BCBR4330

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G K Brown et al.
Journal of inherited metabolic disease, 10(4), 367-375 (1987-01-01)
In addition to the previously reported abnormalities, urine extracts from three cases of succinic semialdehyde dehydrogenase deficiency have shown consistently increased amounts of 2,4-dihydroxybutyric acid, and its lactone, and 3-hydroxypropionic acid, metabolites related to the alpha-oxidation of 4-hydroxybutyric acid. Threo-
M Orešič et al.
Translational psychiatry, 1, e57-e57 (2011-01-01)
Mild cognitive impairment (MCI) is considered as a transition phase between normal aging and Alzheimer's disease (AD). MCI confers an increased risk of developing AD, although the state is heterogeneous with several possible outcomes, including even improvement back to normal
Minna Hartonen et al.
Journal of chromatography. A, 1293, 142-149 (2013-05-07)
Comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry (GC×GC-TOFMS) was applied in the quantification and identification of organic compounds in patient-matched human cerebrospinal fluid (CSF) and serum samples. Concentrations of 21 amino and hydroxyl acids varied from 0.04 to 77ng/μl in CSF
J A Thompson et al.
Clinical chemistry, 21(13), 1892-1898 (1975-12-01)
Gas chromatographic/mass spectrometric/computer analyses of trimethylsilyl derivatives of urine extracts, prepared by an anion-exchange procedure, reveal the presence of several tetronic and deoxytetronic acids. Identifications were confirmed by comparing gas-chromatographic methylene unit values and mass spectrometric characteristics with those of
Bobbie-Jo Webb-Robertson et al.
Metabolomics : Official journal of the Metabolomic Society, 10(5), 897-908 (2014-09-26)
Urease pre-treatment of urine has been utilized since the early 1960s to remove high levels of urea from samples prior to further processing and analysis by gas chromatography-mass spectrometry (GC-MS). Aside from the obvious depletion or elimination of urea, the
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