Skip to Content
Merck
All Photos(3)

Key Documents

View All Documentation

Safety Information

861340

Sigma-Aldrich

Thionin acetate salt

certified by the Biological Stain Commission, Dye content ≥85 %

Synonym(s):

3,7-Diamino-5-phenothiazinium acetate, Lauth’s violet

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Empirical Formula (Hill Notation):
C12H9N3S · C2H4O2
CAS Number:
78338-22-4
Molecular Weight:
287.34
Colour Index Number:
52000
Beilstein:
4345073
MDL number:
MFCD00081194
UNSPSC Code:
12171500
PubChem Substance ID:
24888537
NACRES:
NA.47

grade

certified by the Biological Stain Commission

Quality Level

200

form

powder

composition

Dye content, ≥85%

technique(s)

microbe id | staining: suitable

λmax

598 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CC([O-])=O.Nc1ccc2nc3ccc(N)cc3[s+]c2c1

InChI

1S/C12H10N3S.C2H4O2/c13-7-1-3-9-11(5-7)16-12-6-8(14)2-4-10(12)15-9;1-2(3)4/h1-6H,13-14H2;1H3,(H,3,4)/q+1;/p-1

InChI key

OWXBIRAFHWASMS-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

General description

Thionin is a diaminothiazine, metachromatic cationic dye.

Application

Thionin is widely used as a biological stain, especially in histology. It has been used in the Nissl stain for the labeling of neuronal cell bodies.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

861340-25G:
861340-2.5G:
861340-VAR:
861340-5G:
861340-BULK:
861340-500G:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCM9285
MKCL1525
MKCH8482
MKCC9348
MKBZ4683V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Contribution of carbohydrate histochemistry to glycobiology.
Danguy A, et al.
Histology and Histopathology, 9, 155-155 (1994)
Cerebellar Purkinje cell neurodegeneration after cardiac arrest: effect of therapeutic hypothermia.
Paine MG, et al.
Resuscitation, 83, 1511-1511 (2012)
Jingman Han et al.
Biosensors & bioelectronics, 47, 243-247 (2013-04-16)
Here we report a one-step approach to synthesize graphene oxide-thionine-Au (GO-Thi-Au) nanocomposites using the synergistic effect of Thi and GO. Thi molecules adsorbed on the nanocomposites still kept the property of electroactive redox. Meanwhile, the resulting Au nanoparticles (AuNPs) of
Shujun Yu et al.
Biosensors & bioelectronics, 48, 224-229 (2013-05-22)
A highly sensitive label-free immunosensor for the detection of kanamycin had been developed using silver hybridized mesoporous ferroferric oxide nanoparticles (Ag@Fe₃O₄ NPs) and thionine mixed graphene sheet (TH-GS). TH was used as an electron transfer mediator. The electrical signal was
Wen Li et al.
Analytical chemistry, 84(17), 7583-7590 (2012-08-14)
Site-specific identification of DNA methylation and assay of MTase activity are important in determining specific cancer types, providing insights into the mechanism of gene repression, and developing novel drugs to treat methylation-related diseases. This work reports an electrochemical method for
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service