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Safety Information

69732

Millipore

Lithium mupirocin Supplement

suitable for microbiology,

Selectively inhibits the growth of lactic acid bacteria

Synonym(s):

Lithium mupirocin solution, Li-MUP, MUP supplement

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About This Item

Empirical Formula (Hill Notation):
C26H43LiO9
CAS Number:
73346-79-9
Molecular Weight:
506.56
MDL number:
MFCD11977847
UNSPSC Code:
41171614
PubChem Substance ID:
329761909
NACRES:
NA.85

Agency

ISO 29981:2010

Quality Level

100

sterility

sterile (Filtered and Aseptic Handled)
sterile

form

liquid

shelf life

limited shelf life, expiry date on the label

application(s)

environmental
food and beverages
microbiology

storage temp.

2-8°C

suitability

Lactobacillus spp.
Lactococcus spp.
Leuconostoc spp.
Streptococcus spp.

SMILES string

[Li+].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@H]2CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)[C@H](O)[C@@H]2O

InChI

1S/C26H44O9.Li/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27;/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29);/q;+1/p-1/b16-13+;/t17-,18-,19-,20-,21-,24+,25-,26-;/m0./s1

InChI key

XFIKMPRBSORKQP-JATHGWPISA-M

Related Categories

General description

Lithium mupirocin is isolated from Pseudomonas fluorescens. At lower concentrations, it has bacteriostatic characteristics, while at higher concentrations it is bacteriocidal. Mupirocin is active against gram-positive bacteria such as Methicillin-resistant Staphylococcus aureus (MRSA), Lactobacilli, Lactococci, Streptococci and Leuconostocs. Mupirocin has been used to study mupirocin resistance in Mycoplasma bacteria. Mupirocin inhibits the isoleucyl-tRNA synthetase, which finally results in inhibition of protein and RNA synthesis. Mupirocin lithium salt is freely soluble in water.

Application

Lithium mupirocin supplement is used for selective enumeration of Bifidobacteria from fermented milk products along with the TOS-propionate agar according to ISO 29981:2010 and IDF 220:2010

Components

Composition:
(5ml, sufficient for 100 ml medium)
Mupirocin 5 mg
sterile distilled water 5.0 ml

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

69732-VAR:
69732-10X25ML:
69732-BULK:
69732-25ML:
69732-10X5ML:
69732-5ML:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG6315
BCCF8675
BCCF0698
BCCD5479
BCCD2365

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Variation, viability and validity of bifidobacteria in fermented milk products.
Raeisi, Shahram Naghizadeh, et al.
Food Control, 34, 691-697 (2013)
J Gilbart et al.
Antimicrobial agents and chemotherapy, 37(1), 32-38 (1993-01-01)
Mupirocin resistance in Staphylococcus aureus results from changes in the target enzyme, isoleucyl-tRNA synthetase (IRS). Twelve strains of S. aureus comprising four susceptible (MICs < or = 4 micrograms/ml), four intermediate level-resistant (MICs between 8 and 256 micrograms/ml), and four
Krešimir Matanovic et al.
Journal of clinical microbiology, 51(3), 1005-1007 (2012-12-28)
The genetic analysis of high-level mupirocin resistance (Hi-Mup(r)) in a Staphylococcus pseudintermedius isolate from a dog is presented. The Hi-Mup(r) ileS2 gene flanked by a novel rearrangement of directly repeated insertion sequence IS257 elements was located, together with the aminoglycoside
Sapna Mehta et al.
Clinical orthopaedics and related research, 471(7), 2367-2371 (2013-02-21)
Hospital-acquired infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a source of morbidity and mortality. S. aureus is the most common pathogen in prosthetic joint infections and the incidence of MRSA is increasing. The purposes of this study were (1)
M Lepainteur et al.
The Journal of hospital infection, 83(4), 333-336 (2013-02-19)
In neonatal intensive care units, topical agents represent an increasing part of the infection control armamentarium. Fifty-one coagulase-negative staphylococci (CNS) isolated from catheter-associated bloodstream infections in very preterm neonates were investigated in this study: 41.2% exhibited decreased susceptibility to at
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