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Key Documents

Safety Information

52630

Sigma-Aldrich

Hexamethyldisiloxane

puriss., ≥98.5% (GC)

Synonym(s):

HMDSO

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About This Item

Linear Formula:
(CH3)3SiOSi(CH3)3
CAS Number:
Molecular Weight:
162.38
Beilstein:
1736258
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.22

vapor density

>1 (vs air)

Quality Level

grade

puriss.

Assay

≥98.5% (GC)

form

liquid

refractive index

n20/D 1.377 (lit.)
n20/D 1.377

bp

101 °C (lit.)

mp

−59 °C (lit.)

density

0.764 g/mL at 20 °C (lit.)

SMILES string

C[Si](C)(C)O[Si](C)(C)C

InChI

1S/C6H18OSi2/c1-8(2,3)7-9(4,5)6/h1-6H3

InChI key

UQEAIHBTYFGYIE-UHFFFAOYSA-N

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General description

HMDSO(hexamethyldisiloxane) is an organosilicon compound. It is a non-toxic, environmentally friendly monomer. It can be used as a precursor to synthesize organosilicon thin films. It serves as a silylating agent for carboxylic acids and alcohols. Additionally, it is used in the preparation of aroyl chlorides. HMDSO is commonly used as a water-repellent.

Application

Hexamethyldisiloxane is used:
  • As a modifying agent in the presence of ethanol/n-hexane solution for the preparation of hydrophobic and hydrophilic sodium silicate-based silica xerogels.
  • To form the dielectric layers in the MIM(metal-insulator-metal) structure that is consisting of graphene quantum dots(GQDs) to prepare two-terminal NVM (non-volatile-memory) devices.

Features and Benefits

Hexamethyldisiloxanehas high thermal stability.

Other Notes

For a facile silylation of carboxylic acids; As chloride anion acceptor in the synthesis of sulphinic esters

Pictograms

FlameEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

21.2 °F - closed cup

Flash Point(C)

-6 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

52630-500ML:
52630-BULK:
52630-100ML:
52630-1L:
52630-VAR:


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H. Matsumoto et al.
Chemistry Letters (Jpn), 1475-1475 (1980)
J. Drabowicz
Chemistry Letters (Jpn), 1753-1753 (1981)
J. Heberle et al.
Silylating Agents, 2nd ed. (1995)
Pavel Solař et al.
Scientific reports, 7(1), 8514-8514 (2017-08-19)
Nanoparticles composed of multiple silver cores and a plasma polymer shell (multicore@shell) were prepared in a single step with a gas aggregation cluster source operating with Ar/hexamethyldisiloxane mixtures and optionally oxygen. The size distribution of the metal inclusions as well
Anastasia Spyrogianni et al.
Journal of colloid and interface science, 507, 95-106 (2017-08-07)
The surface chemistry of synthetic amorphous silicas is essential for their applicational performance and for understanding their interactions with biological matter. Synthesis of silica by flame spray pyrolysis (FSP) allows to control the content and type of hydroxyl groups which

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