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Key Documents

Safety Information

49909

Sigma-Aldrich

Lanolin

tested according to Ph. Eur.

Synonym(s):

Adeps lanae, Wool fat

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About This Item

CAS Number:
8006-54-0
EC Number:
232-348-6
MDL number:
MFCD00081740
UNSPSC Code:
12352211
NACRES:
NA.25

Agency

USP/NF
tested according to Ph. Eur.

Quality Level

100

autoignition temp.

833 °F

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General description

Lanolin is a wool fat. It is a semisolid of high viscosity. Contact allergy to lanolin (wool alcohols), an important sensitizer, in a central London teaching hospital patch-test population has been reported. Simplified extraction of organochlorine and organophosphorus pesticides, frequently found in lanolin, has been proposed. It is utilized as an emulsifier in pharmaceutical and cosmetic formulations.

Application

Lanolin was used to compose the lanolin ointment to estimate the release kinetics of izotretinon and heparin from various semisolid dosage forms by UV-VIS spectroscopy. It was used to prepare the emulsified aqueous solutions containing crystalline dicarboxylic acid. It may be added as excipient to compose a nanoscale-dispersed eye ointment (NDEO) for the treatment of severe evaporative dry eye.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

49909-VAR-F:
49909-BULK-F:
49909-1KG-F:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ5028
BCCH6933
BCCG4689
BCCG1393
BCCF4818

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Oxalic acid as a heterogeneous ice nucleus in the upper troposphere and its indirect aerosol effect.
Zobrist B, et al.
Atmospheric Chemistry and Physics, 6(10), 3115-3129 (2006)
S H Wakelin et al.
The British journal of dermatology, 145(1), 28-31 (2001-07-17)
Lanolin is often stated to be an important sensitizer but some of the available literature is based on the analysis of high-risk patients. To analyse the frequency of contact allergy to lanolin (wool alcohols) in a central London teaching hospital
Flora B de Waard-van der Spek et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 26(7), 598-606 (2015-08-20)
Allergic contact dermatitis (ACD) in children appears to be on the increase, and contact sensitization may already begin in infancy. The diagnosis of contact dermatitis requires a careful evaluation of a patient's clinical history, physical examination, and skin testing. Patch
Wenjian Zhang et al.
Nanotechnology, 25(12), 125101-125101 (2014-02-28)
A novel nanoscale-dispersed eye ointment (NDEO) for the treatment of severe evaporative dry eye has been successfully developed. The excipients used as semisolid lipids were petrolatum and lanolin, as used in conventional eye ointment, which were coupled with medium-chain triglycerides
H Diserens
Journal - Association of Official Analytical Chemists, 72(6), 991-993 (1989-11-01)
In the proposed method, a light petroleum solution of lanolin (wool fat) is adsorbed on diatomaceous earth in an Extrelut column, and the pesticides are eluted with acetonitrile saturated with light petroleum. After evaporation to a small volume, the extract
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