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Safety Information

434760

Sigma-Aldrich

Benzamidine hydrochloride

99%

Synonym(s):

Amidinobenzene hydrochloride, Benzamidinium chloride

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About This Item

Linear Formula:
C6H5C(=NH)NH2 · HCl
CAS Number:
1670-14-0
Molecular Weight:
156.61
Beilstein:
3594959
EC Number:
216-795-4
MDL number:
MFCD00013025
UNSPSC Code:
12352106
PubChem Substance ID:
24867207
NACRES:
NA.77

Quality Level

200

Assay

99%

form

beads

mp

169-173 °C (lit.)

solubility

water: soluble

SMILES string

Cl.NC(=N)c1ccccc1

InChI

1S/C7H8N2.ClH/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H3,8,9);1H

InChI key

LZCZIHQBSCVGRD-UHFFFAOYSA-N

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Application

<ul>
<li><strong>Purification and characterization of a serine protease from organic dust and elucidation of its inductive effects on lung i</strong></li>
<li><strong>Preclinical testing of dabigatran in trypsin-dependent pancreatitis:</strong> This research uses Benzamidine hydrochloride to inhibit serine proteases in models of pancreatitis, highlighting its potential in preclinical studies to evaluate new therapeutic approaches for inflammatory and digestive disorders (Pesei et al., 2022).</li>
</ul>

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

434760-BULK:
434760-VAR:
434760-25G:
434760-5G:

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Certificates of Analysis (COA)

Lot/Batch Number
WXBD2093V
MKCP8738
WXBD5908V
MKCM0636
WXBD1432V

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Seweryn Mroczek et al.
Nature communications, 8(1), 619-619 (2017-09-22)
FAM46C is one of the most frequently mutated genes in multiple myeloma. Here, using a combination of in vitro and in vivo approaches, we demonstrate that FAM46C encodes an active non-canonical poly(A) polymerase which enhances mRNA stability and gene expression.
Bradley S Heater et al.
Biotechnology for biofuels, 12, 165-165 (2019-07-13)
We have recently developed a one-step, genetically encoded immobilization approach based on fusion of a target enzyme to the self-crystallizing protein Cry3Aa, followed by direct production and isolation of the fusion crystals from Bacillus thuringiensis. Using this approach, Bacillus subtilis
Zaofeng Yang et al.
iScience, 23(6), 101158-101158 (2020-05-29)
The effectiveness of cancer radiotherapy is frequently hindered by the hypoxia of the tumor microenvironment. Direct delivery of oxygen to hypoxic tumor tissues is an attractive strategy to overcome this hypoxia-associated radioresistance. Herein, we report the generation of submicron-sized particles
Joris Van Lindt et al.
Communications biology, 4(1), 77-77 (2021-01-21)
Understanding the kinetics, thermodynamics, and molecular mechanisms of liquid-liquid phase separation (LLPS) is of paramount importance in cell biology, requiring reproducible methods for studying often severely aggregation-prone proteins. Frequently applied approaches for inducing LLPS, such as dilution of the protein
Anita de Ruiter et al.
Journal of computational chemistry, 34(12), 1024-1034 (2013-01-22)
The performances of Bennett's acceptance ratio method and thermodynamic integration (TI) for the calculation of free energy differences in protein simulations are compared. For the latter, the standard trapezoidal rule, Simpson's rule, and Clenshaw-Curtis integration are used as numerical integration
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