38332

Scopoletin

analytical standard

• Synonym(s): 6-Methoxyumbelliferone, 6-Methylesculetin, 7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one, 7-Hydroxy-6-methoxycoumarin, Buxuletin, Chrysatropic acid, Escopoletin, Esculetin-6-methyl ether, Gelseminic acid, Murrayetin
• Empirical Formula (Hill Notation): C₁₀H₈O₄
• CAS Number: 92-61-5
• Molecular Weight: 192.17
• Beilstein: 156296
• EC Number: 202-171-9
• MDL number: MFCD00006872
• UNSPSC Code: 85151701
• PubChem Substance ID: 329755673
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• Assay: ≥97.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 203-205 °C (lit.)
• application(s): food and beverages
• format: neat
• storage temp.: 2-8°C
• SMILES string: COc1cc2C=CC(=O)Oc2cc1O
• InChI: 1S/C10H8O4/c1-13-9-4-6-2-3-10(12)14-8(6)5-7(9)11/h2-5,11H,1H3
• InChI key: RODXRVNMMDRFIK-UHFFFAOYSA-N

Description

General description

Scopoletin is a coumarin compound and pharmacologically active chemical that is found in various plant species.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Scopoletin may be used as a reference standard for the determination of scopoletin in:

• Roots, stems, branches, and seeds as well as leaves of Chimonanthus nitens Oliv. by ultra-high performance liquid chromatography/tandem quadrupole-time-of-flight mass spectrometry (UHPLC-QTOF-MS/MS) equipped with modified mass deflect filter or diagnostic product ions/neutral loss filter.
• Canscora decussate (South Indian Shankhpushpi) extracts by high performance thin layer chromatography (HPTLC).
• Morinda tinctoria Roxb. leaf by HPTLC in conjunction with HPLC and gas chromatography with MS.

Biochem/physiol Actions

Scopoletin significantly increases activity of lipoprotein lipase in adipocytes by promoting transcription of the LPL gene. It also partially reverses inhibition of LPL by TNF-α.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable