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Safety Information

31519

Supelco

Ethoxyquin

PESTANAL®, analytical standard

Synonym(s):

1,2-Dihydro-6-ethoxy-2,2,4-trimethylquinoline, 6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline

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About This Item

Empirical Formula (Hill Notation):
C14H19NO
CAS Number:
91-53-2
Molecular Weight:
217.31
Beilstein:
158223
EC Number:
202-075-7
MDL number:
MFCD00023883
UNSPSC Code:
41116107
PubChem Substance ID:
329753793
E Number:
E324
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

density

1.03 g/mL at 20 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

shipped in

wet ice

storage temp.

2-8°C

SMILES string

CCOc1ccc2NC(C)(C)C=C(C)c2c1

InChI

1S/C14H19NO/c1-5-16-11-6-7-13-12(8-11)10(2)9-14(3,4)15-13/h6-9,15H,5H2,1-4H3

InChI key

DECIPOUIJURFOJ-UHFFFAOYSA-N

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General description

Ethoxyquin (EQ), an aromatic compound, is an antioxidant mostly used in animal and fish feeds. It is seen to inhibit carcinogenic effects of polycyclic aromatic hydrocarbons. Oxidation initiated by air, light or transition metals in unsaturated lipids can be stopped from propagation by EQ.

Application

EQ has been used as external standard in the determination of EQ and its major metabolite from Atlantic salmon tissues using HPLC with fluorescence detector.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Caution

Light sensitive: sensitive
Air sensitive: Handle under argon

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class II Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

31519-VAR:
31519-BULK:
31519-250MG:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK2516
BCCD7838
BCCB8125
BCBZ0883
BCBS7214V

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The inhibitory effects of ethoxyquin on the carcinogenic action of aflatoxin B1 in rats.
Cabral JR, Neal GE.
Cancer Letters, 19(2), 125-132 (1983)
Alina Błaszczyk et al.
Chemico-biological interactions, 162(3), 268-273 (2006-09-09)
Four newly synthesized salts of ethoxyquin (EQ: 1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline), an antioxidant used in animal feeds, were evaluated with the use of the comet assay performed on human lymphocytes: ethoxyquin ascorbate, ethoxyquin hexanoate, ethoxyquin salicylate and ethoxyquin salt of Trolox C (6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic
Alina Błaszczyk et al.
Acta poloniae pharmaceutica, 62(2), 111-115 (2005-09-16)
In our study ethoxyquin (EQ) and its two complexes with flavonoids were obtained from ethoxyquin (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline, EQ) and quercetin (EQ-Q, 1:1) or rutin (EQ-R, 1:1). Cytotoxicity of the tested compounds was studied using the trypan blue exclusion method and the
Anup G Shah et al.
Water research, 39(17), 4251-4263 (2005-10-04)
The potential inhibitory effect of ethoxyquin, an antioxidant commonly used as a preservative in the food processing industry (e.g., for stabilizing dissolved air flotation residuals), was evaluated at concentrations up to 300 mg/L using a mixed, mesophilic (35 degrees C)
Alina Błaszczyk
Toxicology letters, 163(1), 77-83 (2005-11-04)
Ethoxyquin (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline, EQ) is widely used in various food products and in animal feeds because of its powerful antioxidant activity. This compound was recently found to cause not only many unfavourable side-effects in animals fed with feeds containing it, but
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