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293105

Sigma-Aldrich

Tetrahydropyran

anhydrous, 99%

Synonym(s):

Pentamethylene oxide

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About This Item

Empirical Formula (Hill Notation):
C5H10O
CAS Number:
142-68-7
Molecular Weight:
86.13
Beilstein:
102436
EC Number:
205-552-8
MDL number:
MFCD00006585
UNSPSC Code:
12352005
PubChem Substance ID:
57648359
NACRES:
NA.21

grade

anhydrous

Quality Level

100

vapor density

3 (vs air)

Assay

99%

form

liquid

impurities

<0.003% water
<0.005% water (100 mL pkg)

evapn. residue

<0.0003%

refractive index

n20/D 1.42 (lit.)

bp

88 °C (lit.)

mp

−45 °C (lit.)

density

0.881 g/mL at 25 °C (lit.)

SMILES string

C1CCOCC1

InChI

1S/C5H10O/c1-2-4-6-5-3-1/h1-5H2

InChI key

DHXVGJBLRPWPCS-UHFFFAOYSA-N

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General description

Tetrahydropyran (THP) is a saturated cyclic ether. It is commonly used as a solvent in organic synthesis because of its strong hydrophobicity and low vaporization temperature, which enable easy recovery and reuse of the solvent. This makes the entire synthetic process more environmentally friendly.

Application

Tetrahydropyran can be used as a solvent in various classical organic reactions such as radical reactions, palladium-catalyzed coupling, and Grignard reactions.

Pictograms

Flame
GHS02

Signal Word

Danger

Hazard Statements

H225

Hazard Classifications

Flam. Liq. 2

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

3.2 °F - closed cup

Flash Point(C)

-16 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

293105-100ML:
293105-2L:
293105-BULK:
293105-VAR:
293105-6X1L:
293105-1L:
293105-4X2L:

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Certificates of Analysis (COA)

Lot/Batch Number
SHBJ6605
SHBJ8467
SHBH9980
SHBF5064V
SHBC9165V

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