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16383

Supelco

Sennoside D

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C42H40O19
CAS Number:
37271-17-3
Molecular Weight:
848.76
UNSPSC Code:
85151701
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

OC[C@H]1O[C@@H](Oc2cccc3[C@@H]([C@H]4c5cccc(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c5C(=O)c7c(O)cc(cc47)C(O)=O)c8cc(CO)cc(O)c8C(=O)c23)[C@H](O)[C@@H](O)[C@@H]1O

Related Categories

General description

Sennoside D is an active constituent of senna which is generally used as a laxative. It belongs to anthranoid family, and is procured from dried leaflets and pods of senna plant.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

16383-10MG:
16383-VAR:
16383-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCC6237
BCBW7896
BCBT3519
BCBP7858V
BCBM7374V

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Analytical studies on the active constituents in crude drugs. IV. Determination of sennosides in senna and formulations by high-performance liquid chromatography.
Hayashi S
Chemical & Pharmaceutical Bulletin, 28(2), 406-412 (1980)
Review article: anthranoid laxatives and their potential carcinogenic effects.
van Gorkom BA
Alimentary Pharmacology & Therapeutics, 13(4), 443-452 (1999)
K Yamauchi et al.
The Journal of pharmacy and pharmacology, 44(12), 973-976 (1992-12-01)
Sennosides A and C directly injected into the caecum of mice showed equal purgative activity. Intracaecal administration reduced time to onset of diarrhoea induced by sennoside C from about 3 h after oral administration to about 24 min. At 2.3
Potentiating effect of sennoside C on purgative activity of sennoside A in mice.
K Kisa et al.
Planta medica, 42(3), 302-303 (1981-07-01)
T Yagi et al.
The Journal of pharmacy and pharmacology, 49(1), 22-25 (1997-01-01)
This study aimed to explore the mechanism involved in the synergistic purgative action of aloe-emodin anthrone and rhein anthrone, the active metabolites of sennoside C. Aloe-emodin anthrone and rhein anthrone, and their equimolar mixture, induced excretion of an approximately equal

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