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Key Documents

Safety Information

08058

Sigma-Aldrich

Carbonate Bicarbonate Buffer with Azide

BioUltra, tablet

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About This Item

UNSPSC Code:
12161700
NACRES:
NA.25

product line

BioUltra

form

tablet

pH

9.6

solubility

water: 1 tablet/100mL, clear, colorless

Application

Carbonate bicarbonate buffer with azide has been used in a study to examine the effects of phorbol myristate acetate on acid secretion by the turtle urinary bladder to evaluate the importance of protein phosphorylation in modulating the distal acidification system. Carbonate bicarbonate buffer with azide has also been used in a study that assessed the effects of pH on bone calcium and proton fluxes in vitro.

Packaging

50 tablets in blister package

Reconstitution

1 tablet in 100 mL of water yields in 0.05 M NaHCO3, 0.05% NaN3, pH 9.6

Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Poisonous substance

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

08058-50TAB-F:4548173287416


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D A Bushinsky et al.
The American journal of physiology, 245(2), F204-F209 (1983-08-01)
Bone mineral is thought to decompose during acute and chronic metabolic acidosis and thereby contribute to buffering of the acid load. We cultured neonatal mouse calvariae for 3 h and found calcium efflux from bone when the medium pH was
Shenghua Huang et al.
PloS one, 6(12), e28458-e28458 (2011-12-14)
The β-class carbonic anhydrases (β-CAs) are widely distributed among lower eukaryotes, prokaryotes, archaea, and plants. Like all CAs, the β-enzymes catalyze an important physiological reaction, namely the interconversion between carbon dioxide and bicarbonate. In plants the enzyme plays an important
M Graber et al.
The American journal of physiology, 257(6 Pt 2), F1124-F1131 (1989-12-01)
The effects of phorbol myristate acetate (PMA) on acid secretion by the turtle urinary bladder were examined to evaluate the importance of protein phosphorylation in modulating the distal acidification system. In HCO3-free PO4 buffer 0.2 mM mucosal PMA inhibited reverse
Petraleigh Pantoja et al.
Nature communications, 8, 15674-15674 (2017-06-24)
Zika virus (ZIKV) is a re-emerging virus that has recently spread into dengue virus (DENV) endemic regions and cross-reactive antibodies (Abs) could potentially affect ZIKV pathogenesis. Using DENV-immune serum, it has been shown in vitro that antibody-dependent enhancement (ADE) of

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