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Safety Information

06676

Sigma-Aldrich

Methoxypolyethylene glycol amine

2,000, extent of labeling: ≥0.4 mmol/g NH2 loading

Synonym(s):

O-(2-Aminoethyl)-O′-methylpolyethylene glycol, Aminopolyethylene glycol monomethyl ether, Methoxypolyoxyethylene amine

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About This Item

Linear Formula:
H2NCH2CH2(OCH2CH2)nOCH3
CAS Number:
80506-64-5
MDL number:
MFCD00131599
UNSPSC Code:
12162002
PubChem Substance ID:
24845957
NACRES:
NA.22

Quality Level

100

form

powder

extent of labeling

≥0.4 mmol/g NH2 loading

InChI

1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3

InChI key

ASUDFOJKTJLAIK-UHFFFAOYSA-N

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Application

Methoxypolyethylene glycol amine (mPEG-NH2) can be used:
  • As a supporting material in the synthesis of polymer-lipid conjugates.
  • As an initiator for ring-opening polymerization (ROP) of N-substituted N-carboxy anhydrides (NNCAs) to prepare polypeptoids.

Other Notes

Soluble polymer support for peptide synthesis; Preparation of various conjugates containing polyethylene glycol; Review

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

06676-VAR:
06676-BULK:
06676-250MG:
06676-1G:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG4637
BCCD8178
BCCC5286
BCCC0653
BCCB6113

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Schiff base and reductive amination reactions of α-amino acids: a facile route toward N-alkylated amino acids and peptoid synthesis
Fu X, et al.
Polym. Chem., 9(37), 4617-4624 (2018)
M. Mutter et al.
Reactive Polymers, 6, 99-99 (1987)
Synthesis of Poly (ethylene glycol)-Polydiacetylene Conjugates and Their Micellar and Chromic Characteristics
Choi H et al.
Journal of Nanoscience and Nanotechnology, 8(10), 5104-5108 (2008)
R Colombo et al.
Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 362(10), 1385-1391 (1981-10-01)
The liquid-phase synthesis of two pentapeptides corresponding to the amino acid sequence of Leu- and Met-enkephalin is described. Modified monofunctional poly(ethylene glycol) containing a p-alkoxybenzyl alcohol functional group was employed as the soluble polymeric support. Cleavage of the peptides from
M. Leonard et al.
Tetrahedron, 40, 1581-1581 (1984)
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