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Key Documents

Safety Information

04100

Sigma-Aldrich

Ethylhydrazine oxalate

≥96.0% (T)

Synonym(s):

Ethylhydrazine ethanedioate

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About This Item

Empirical Formula (Hill Notation):
C2H8N2 · C2H2O4
CAS Number:
Molecular Weight:
150.13
Beilstein:
3697941
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥96.0% (T)

impurities

~2% hydrazine

mp

170-173 °C (dec.)

functional group

amine
carboxylic acid
hydrazine

SMILES string

CCNN.OC(=O)C(O)=O

InChI

1S/C2H8N2.C2H2O4/c1-2-4-3;3-1(4)2(5)6/h4H,2-3H2,1H3;(H,3,4)(H,5,6)

InChI key

DUMHBFMURBWDPC-UHFFFAOYSA-N

Application

Ethylhydrazine oxalate can be used to synthesize:
  • 1-ethyl-1H-indazoles
  • 3-substituted 1-ethyl-6-methylpyrimido[4,5-c]pyridazine-5,7(1H,6H)-dione derivatives
  • 4-(2-alkyl-5-methyl-2H-pyrazol-3-yl)-piperidines

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1B - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

PRTR

Class I Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

04100-25G:4548173230399
04100-VAR:
04100-INTR:
04100-5G:4548173230382
04100-BULK:


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Parallel Synthesis of Novel 3-Substituted 1-Ethyl-6-methylpyrimido [4, 5-c] pyridazine-5, 7 (1 H, 6 H)-dione Analogs.
Chen Y, et al.
Synthetic Communications, 40(6), 821-832 (2010)
Regioselective synthesis of 4-(2-alkyl-5-methyl-2H-pyrazol-3-yl)-piperidines.
Dirat O, et al.
Tetrahedron Letters, 47(11), 1729-1731 (2016)
A method for the regioselective synthesis of 1-alkyl-1H-indazoles.
Liu HJ, et al.
Tetrahedron, 69(19), 3907-3912 (2013)
Giorgio Ramadori et al.
Cell reports, 30(11), 3851-3863 (2020-03-19)
Cancer therapy is limited, in part, by lack of specificity. Thus, identifying molecules that are selectively expressed by, and relevant for, cancer cells is of paramount medical importance. Here, we show that peptidyl-prolyl-cis-trans-isomerase (PPIase) FK506-binding protein 10 (FKBP10)-positive cells are

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