SCC273
C57MG Mouse Mammary Epithelial Cell Line
C57MG mouse mammary epithelial cell line is a useful model system for studies of breast cancer malignancy.
About This Item
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application(s)
cell analysis
General description
The C57MG immortalized mammary epithelial cell line is an established model for mammary epithelial malignancy. C57MG cells are syngeneic with the C57BL/6 mouse model and have demonstrated potential of transformation with many proto-oncogenic factors. The C57MG cell line is widely used in studies of the role of Wnt signaling in malignant transformation (4). C57MG cells have been shown to upregulate expression of proto-oncogenic β-catenin in response to Wnt proteins (5). The features of the C57MG cell line make it a highly relevant model system for studies of breast cancer malignancy.
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The C57MG cell line was established from mammary epithelial tissue of a C57BL/6 mouse (2).
Research Category:
Cancer
Cell Line Origin
Packaging
Storage and Stability
Other Notes
Disclaimer
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Regulatory Listings
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JAN Code
SCC273:
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