MAP2MAG-76K

MILLIPLEX^® Mouse Acute Phase Magnetic Bead Panel 2 - Cardiovascular Disease Multiplex Assay

The analytes available for this multiplex kit are: Adipsin, Alpha-1 Acid Glycoprotein (AGP), Alpha-2 Macroglobulin (A2M), C-Reactive Protein, Haptoglobin, SAP.

• UNSPSC Code: 12161503
• eCl@ss: 32161000

Properties

• Quality Level: 200
• species reactivity: mouse
• manufacturer/tradename: Milliplex^®
• assay range: accuracy: 99.2-128.2%; sensitivity: 0.001-7.495 ng/mL; standard curve range: 0.001-0.5 ng/mL; (AGP); standard curve range: 0.005-4.0 ng/mL; (Adipsin); standard curve range: 0.014-10 ng/mL; (CRP); standard curve range: 0.549-400 ng/mL; (Haptoglobin); standard curve range: 13.717-10,000 ng/mL; (SAP); standard curve range: 6.858-5000 ng/mL; (A2M); inter-assay cv: <15%; intra-assay cv: <10%
• technique(s): multiplexing: suitable
• detection method: fluorometric (Luminex xMAP)
• shipped in: wet ice

Description

General description

Acute phase proteins are a class of proteins whose circulating concentrations increase (positive acute phase proteins) or decrease (negative acute phase proteins) in response to inflammation. This response is called the acute phase reaction or acute phase response. In recent years several new acute phase proteins have been identified, some of which are secreted from adipose tissue.

MILLIPLEX^® Mouse Acute Phase Magnetic Bead Panel 2 is a 6-plex kit to be used for the simultaneous quantification of any or all of the following analytes in mouse serum or plasma samples, mouse tissue extract, or cell/tissue culture supernatant samples: Adipsin (Complement Factor D), Alpha-1 Acid Glycoprotein (AGP), C-Reactive Protein (CRP), Haptoglobin (HPTGN), Alpha-2 Macroglobulin (A2M) and Serum Amyloid Protein/Pentraxin-2 (SAP). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex^® xMAP^® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Cardiovascular

Specificity

Cross Reactivty
Antibody pairs in the panel are specific and demonstrate no cross-reactivity (<0.1%) with
other analytes in the panel.

Application

• Analytes: α-1, Acid Glycoprotein (AGP), α-2 Macroglobulin (A2M), Adipsin (Factor D), C-Reactive Protein (CRP), Haptoglobin, Serum Amyloid P (SAP)
• Recommended Sample Type: Mouse serum, plasma or cell/tissue culture supernatants lysates
• Recommended Sample Dilution: 25 μL per well of 1:20,000 diluted serum or plasma; cell/tissue culture samples may require dilution in appropriate control medium
• Assay Run Time: Overnight (16-22 hours) at 2-8°C
• Research Category: Cardiovascular
• Research Subcategory: Metabolism

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

Legal Information

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Safety Information

• Pictograms: GHS05,GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H302 + H332 - H311 - H317 - H318 - H373 - H411
• Precautionary Statements: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• Target Organs: Respiratory Tract
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3