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Safety Information

MABT51

Sigma-Aldrich

Anti-Galectin-3 Antibody, clone M3/38

clone M3/38, from rat

Synonym(s):

lectin, galactoside-binding, soluble, 3, Mac-2 antigen, Carbohydrate-binding protein 35, galectin-3, Galactose-specific lectin 3, Laminin-binding protein, Lectin L-29, IgE-binding protein, Galactoside-binding protein

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rat

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

M3/38, monoclonal

species reactivity

mouse, human

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG2aκ

NCBI accession no.

NP_001139425

UniProt accession no.

P16110

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... LGALS3(3958)

General description

Galectin-3 belongs to the galectin gene family defined by the specificity of a carbohydrate recognition domain (CRD) for Gal/Lac and expression is usually elevated in a wide range of neoplastic cell types. The galectin CRD consists of 135 amino acids. Galectin-3 has been shown to effect tumor development and progression.

Immunogen

Plasma membrane glycoproteins corresponding to mouse Galectin-3.

Application

Anti-Galectin-3 Antibody, clone M3/38 is an antibody against Galectin-3 for use in WB, IP, IH & IC.
Western Blot Analysis: 1:50,000 dilution from a previous lot detected Galectin-3 in 10 µg of NIH/3T3 cell lysate.

Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP. (Springer, T., et al. (1981). THE JOURNAL OF BIOLOGICACHLE MISTRY. 256(8):3833-3839.)

Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH. (Gasbarri, A., et al. (1999). Journal of Clinical Oncology. 17(11):3494-3502.)

Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC. (Gasbarri, A., et al. (1999). Journal of Clinical Oncology. 17(11):3494-3502.)

Quality

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1:50,000 dilution of this antibody detected Galectin-3 in 10 µg of HeLa cell lysate.

Target description

~28 kDa observed

Physical form

Format: Purified

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MABT51:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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