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Safety Information

MAB979

Sigma-Aldrich

Anti-Enterovirus 71 Antibody, cross-reacts with Coxsackie A16, clone 422-8D-4C-4D

ascites fluid, clone 422-8D-4C-4D, Chemicon®

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

300

antibody form

ascites fluid

clone

422-8D-4C-4D, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable

isotype

IgG1

shipped in

wet ice

Specificity

Reacts with Enterovirus 71. Neutralizes enterovirus 71 BrCr strain at a titer of less than 1:14.

Immunogen

Epitope: cross-reacts with Coxsackie A16

Application

Indirect immunofluorescence at 1:1,000.

(Also cross-reacts with Coxsackie A16).

Optimal working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
This Anti-Enterovirus 71 Antibody, cross-reacts with Coxsackie A16, clone 422-8D-4C-4D is validated for use in IF for the detection of Enterovirus 71.

Physical form

Ascites fluid containing no preservatives.
Unpurified

Storage and Stability

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Enterovirus Control Slides, Catalogue Number 5066

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB979:
MAB979-KL:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rei-Lin Kuo et al.
PloS one, 8(5), e63431-e63431 (2013-05-08)
Induction of type-I interferons (IFNs), IFN-α/β, is crucial to innate immunity against RNA virus infection. Cytoplasmic retinoic acid-inducible gene I (RIG-I)-like receptors, including RIG-I and melanoma differentiation-associated gene 5 (MDA5), are critical pathogen sensors for activation of type-I IFN expression
Immunological and biochemical characterization of coxsackie virus A16 viral particles.
Chong, P; Guo, MS; Lin, FH; Hsiao, KN; Weng, SY; Chou, AH; Wang, JR; Hsieh, SY; Su, IJ; Liu, CC
Testing null
A novel universal neutralizing monoclonal antibody against enterovirus 71 that targets the highly conserved "knob" region of VP3 protein.
Kiener, TK; Jia, Q; Meng, T; Chow, VT; Kwang, J
PLoS Neglected Tropical Diseases null
Methylene blue-mediated photodynamic inactivation as a novel disinfectant of enterovirus 71.
Wong, TW; Huang, HJ; Wang, YF; Lee, YP; Huang, CC; Yu, CK
The Journal of Antimicrobial Chemotherapy null
Purification and characterization of enterovirus 71 viral particles produced from vero cells grown in a serum-free microcarrier bioreactor system.
Liu, CC; Guo, MS; Lin, FH; Hsiao, KN; Chang, KH; Chou, AH; Wang, YC; Chen, YC; Yang, CS; Chong, PC
Testing null
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