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Safety Information

MAB8754

Sigma-Aldrich

Anti-Eastern Equine Encephalitis Antibody, Virus, clone 1A4B.6

clone 1A4B.6, Chemicon®, from mouse

Synonym(s):

EEE

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

300

antibody form

purified immunoglobulin

clone

1A4B.6, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable
inhibition assay: suitable (hemagglutination)

isotype

IgG2b

shipped in

wet ice

Specificity

The MAb 1A4B-6 is an IgG2b antibody that reacts with an
E1 epitope shared by all alphaviruses. Encephalitis Virus: Strains Indentified:

Eastern Equine (EEE) N. American eastern equine (NJ/60);

S. American eastern equine (BeAn 5122)

Western Equine (WEE) Western equine (McMIllan); Highlands J (B-230);

Sindbis

Semliki Forest Semliki Forest

Venezuelan Equine (VEE) 1AB (TC-83 Vaccine, Trinidad Donkey, PTF-39);

1C (P676); 1D (3880); 1E ( Mena II);

1F(78V-3531); 2 (Fe3-7c); 3 (Mucambo);

4 (Pixuna); 5 (Cabassou)

Immunogen

Epitope: Virus

Application

Detect the Eastern Equine Encephalitis protein using this Anti-Eastern Equine Encephalitis, Virus, clone 1A4B.6 validated for use in ELISA, IF & Hemagglutination Inhibition.
ELISA

Indirect Immunofluorescence

Hemagglutination Inhibition

Optimal working dilutions must be determined by end user.

Physical form

Format: Purified
Purified immunoglobulin. Liquid in PBS with 0.1% Sodium Azide.

Storage and Stability

Maintain at 2 to 8°C for up to 12 months from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB8754-KL:
MAB8754:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Japanese encephalitis among hospitalized pediatric and adult patients with acute encephalitis syndrome in Hanoi, Vietnam 1995.
Lowry, P W, et al.
The American Journal of Tropical Medicine and Hygiene, 58, 324-329 (1998)
Detection of eastern equine encephalitis virus in infected mosquitoes using a monoclonal antibody-based antigen-capture enzyme-linked immunosorbent assay
Brown, T M, et al
The American Journal of Tropical Medicine and Hygiene, 65, 208-213 (2001)
Efficient functional pseudotyping of oncoretroviral and lentiviral vectors by Venezuelan equine encephalitis virus envelope proteins
Kolokoltsov, Andrey A, et al
Journal of virology, 79, 756-763 (2005)
A J Johnson et al.
Journal of clinical microbiology, 38(5), 1827-1831 (2000-05-02)
Monoclonal antibody (MAb)-based capture enzyme-linked immunosorbent assays (ELISAs) for the detection of anti-arboviral immunoglobulin G (IgG ELISAs) were developed for a comprehensive array of medically important arboviruses from the Alphavirus, Flavivirus, and Bunyavirus genera. Tests were optimized and standardized so
JinZhu Ma et al.
Biotechnology journal, 16(8), e2100008-e2100008 (2021-06-28)
Western equine encephalitis virus (WEEV) causes lethal encephalitis in humans and equines, and it poses a serious public health threat in many countries. Therefore, the development of an efficient vaccine remains an important challenge for the prevention of WEEV infection.
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