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MAB5620

Sigma-Aldrich

Anti-Norepinephrine Transporter Antibody

ascites fluid, Chemicon®

Synonym(s):

NET

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

monoclonal

species reactivity

human, monkey

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

isotype

IgG

NCBI accession no.

NM_001043.2

UniProt accession no.

P23975

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SLC6A2(6530) , SLC6A5(9152)

Specificity

Norepinephrine Transporter, human and non-human primate.

Immunogen

Synthetic peptide from human norepinephrine Transporter.

Application

Detect Norepinephrine Transporter using this Anti-Norepinephrine Transporter Antibody validated for use in IH.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB5620:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Deborah C Mash et al.
Journal of neuroscience methods, 143(1), 79-85 (2005-03-15)
The norepinephrine transporter (NET) is a membrane protein responsible for transporting extracellular norepinephrine. The cocaine and tricyclic antidepressant-sensitive NET belongs to a family of sodium and chloride coupled transporters that include the monoamines dopamine and serotonin and the amino acids
Maureen K Hahn et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 23(11), 4470-4478 (2003-06-14)
The norepinephrine transporter (NET) mediates reuptake of norepinephrine released from neurons, and, as such, it is an important regulator of noradrenergic neurotransmission. Recently, our laboratory reported a polymorphism in the human NET (hNET) gene A457P in an individual with the
Trafficking-dependent and -independent pathways of neurotransmitter transporter regulation differentially involving p38 mitogen-activated protein kinase revealed in studies of insulin modulation of norepinephrine transport in SK-N-SH cells.
Apparsundaram, S, et al.
Journal of Pharmacology and Experimental Therapeutics, 299, 666-677 (2001)
Norepinephrine induces endoplasmic reticulum stress and downregulation of norepinephrine transporter density in PC12 cells via oxidative stress
Mao, Weike, et al
American Journal of Physiology. Heart and Circulatory Physiology, 288, H2381-H2389 (2005)
Katherine L Holton et al.
Nature neuroscience, 8(7), 881-888 (2005-06-01)
Neurotransmitter transporters are critical for synaptic neurotransmitter inactivation. Transporter inhibitors markedly increase the duration and magnitude of synaptic transmission, underscoring the importance of transporter activity in neurotransmission. Recent studies indicate that membrane trafficking dynamically governs neuronal transporter cell-surface presentation in
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