Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

MAB5578

Sigma-Aldrich

Anti-NMDAR2D Antibody

ascites fluid, clone 1G9.39A5, Chemicon®

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

ascites fluid

clone

1G9.39A5, monoclonal

species reactivity

human, mouse, rat, rabbit

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

isotype

IgG2b

NCBI accession no.

NM_000836.2

UniProt accession no.

O15399

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... GRIN2D(2906)

Specificity

NMDAR2D, C-terminal. By Western blot the antibody reacts with a weak band at ~145. An additional band at ~75 kDa may be seen depending on sample and antibody concentration used.

Immunogen

Recombinant protein from rat NMDAR2D.

Application

Anti-NMDAR2D Antibody detects level of NMDAR2D & has been published & validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Western blot: 1:500-1:1,000 on rat brain lysate.

Optimal working dilutions must be determined by end user.

Physical form

Liquid.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Analysis Note

Control
Rat forebrain or cerebellum.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB5578:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Sharon A Swanger et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(48), 15971-15983 (2015-12-04)
The GluN2D subunit of the NMDA receptor is prominently expressed in the basal ganglia and associated brainstem nuclei, including the subthalamic nucleus (STN), globus pallidus, striatum, and substantia nigra. However, little is known about how GluN2D-containing NMDA receptors contribute to
Gajanan P Shelkar et al.
Scientific reports, 9(1), 7572-7572 (2019-05-22)
The GluN2C- and GluN2D-containing NMDA receptors are distinct from GluN2A- and GluN2B-containing receptors in many aspects including lower sensitivity to Mg2+ block and lack of desensitization. Recent studies have highlighted the unique contribution of GluN2C and GluN2D subunits in various
D J Laurie et al.
Brain research. Molecular brain research, 51(1-2), 23-32 (1998-01-14)
Mouse monoclonal antibodies were raised against bacterially expressed protein sequences of the NR2A, NR2B, NR2C and NR2D subunits of the rat NMDA receptor. From immunoblots of rat brain proteins, the apparent molecular weights of these subunits were 165, 170, 135
Jinxu Liu et al.
Neurobiology of disease, 150, 105254-105254 (2021-01-10)
Globus pallidus externa (GPe) is a nucleus in the basal ganglia circuitry involved in the control of movement. Recent studies have demonstrated a critical role of GPe cell types in Parkinsonism. Specifically increasing the function of parvalbumin (PV) neurons in
Jeremy S Lum et al.
Neurochemical research, 43(8), 1683-1691 (2018-06-25)
Dysfunction of the glutamatergic system is believed to underlie many neurodevelopmental disorders including autism, Rett syndrome and schizophrenia. Metabotropic glutamate receptor (mGluR5) positive allosteric modulators (PAM) potentiate glutamatergic signaling, particularly indirectly via the NMDA receptor. Preclinical studies report mGluR5 PAMs
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service