MAB5456-C
Anti-Gonadotropin-Releasing Hormone Antibody, NT, clone HU11B (Ascites Free)
clone HU11B, from mouse
Synonym(s):
Gonadotropin-releasing hormone I, GnRH-I, Luliberin I, Luteinizing hormone-releasing hormone I, LH-RH I
About This Item
Recommended Products
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
HU11B, monoclonal
species reactivity
human, rat, rhesus macaque, mouse
technique(s)
affinity binding assay: suitable
electron microscopy: suitable
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... GNRH1(2796)
General description
Specificity
Immunogen
Application
Affinity Binding Assay: A representative lot captured C-terminally blocked GnRH-I/LHRH (LHRH-NH2), but not LHRH with a free C-terminal end (LHRH-COOH). Clone HU11B exhibited reduced affinity toward N-terminally truncated LHRH-NH2 and failed to recognize pro-LHRH, Atrial Naturetic Factor/ANF, Growth hormone-releasing hormone/GHRH, Oxytocin, Somatostatin, Thyrotropin-releasing hormone/TRH, and Vasoactive intestinal peptide/VIP (Urbanski, H.F., et al. (1991). Biol. Reprod. 44(4):681-686).
Immunofluorescence Analysis: A representative lot detected GnRH neurons in brain sections from female rhesus monkeys by fluorescent immunohistochemistry (Naugle, M.M., and Gore, A.C. (2014). Neuroendocrinology 100:334-346).
Immunofluorescence Analysis: A representative lot detected pregnancy stage-dependent GnRH-I immunoreactivity in the luminal epithelium of rat oviduct by fluorescent immunohistochemistry using paraformaldehyde-fixed cryosections (Sengupta, A., et al. (2007). J. Histochem. Cytochem. 55(5):525-534).
Immunofluorescence Analysis: A representative lot detected GnRH-I immunoreactivity in frozen mouse hypothalamic sections by fluorescent immunohistochemistry (Olcese, J., et al. (2003). Neuroreport. 14(4):613-618).
Electron Microscopy: A representative lot detected GnRH-I immunoreactivity associated with the luminal epithelium secretory vesicles of rat oviduct by EM using paraformaldehyde-fixed LR wihite sections from rats at day 16 of pregnancy (Sengupta, A., et al. (2007). J. Histochem. Cytochem. 55(5):525-534).
Immunohistochemistry Analysis: A representative lot detected GnRH-I immunoreactivity throughout the hypothalamus in paraformalin-fixed, paraffin-embedded South American plains vizcacha (Lagostomus maximus) brain sections (Dorfman, V.B., et al. (2011). J. Mol. Histol. 42(4):311-321).
Immunohistochemistry Analysis: A representative lot detected GnRH-I-positie neurons in formalin-fixed, paraffin-embedded mouse brain sections (Bergman, J.E., et al. (2010). Eur. J. Hum. Genet. 18(2):171-177).
Immunohistochemistry Analysis: A representative lot detected GnRH-I immunoreactivity in paraformaldehyde-fixed rat brain vibratome sections (Urbanski, H.F., et al. (1991). Biol. Reprod. 44(4):681-686).
Neuroscience
Developmental Neuroscience
Quality
Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected Gonadotropin-Releasing Hormone in human prostate tissue.
Target description
Physical form
Storage and Stability
Other Notes
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Listings
Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.
JAN Code
MAB5456-C:
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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