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Safety Information

MAB3315

Sigma-Aldrich

Anti-MMP-7 Antibody, clone 141-7B2

clone 141-7B2, Chemicon®, from mouse

Synonym(s):

Matrilysin

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

clone

141-7B2, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

isotype

IgG1κ

NCBI accession no.

NM_002423.3

UniProt accession no.

P09237

shipped in

dry ice

target post-translational modification

unmodified

Specificity

The antibody specifically reacts with precursor form of human MMP-7. Does not cross-react with the active forms of human MMP-7 and human MMP-1, 2, 3, 8, 9 and 13.

Immunogen

Rectal carcinoma (SW837) cells.

Application

Anti-MMP-7 Antibody, clone 141-7B2 is an antibody against MMP-7 for use in ELISA, WB, IH(P).
Immunoblotting: 10 μg/mL Molecular weight band around 30kDa.

Immunohistochemistry on paraffin-embedded tissue sections: 4-20 μg/mL

EIA

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
MMPs & TIMPs

Physical form

Format: Purified
Purified immunoglobulin. Liquid in 0.1 M sodium phosphate buffer, pH 7.0 containing 2% protease-free bovine serum albumin.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Manufactured by Daiichi Fine Chemical Co., Ltd

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB3315:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yali Zhai et al.
The American journal of pathology, 160(4), 1229-1238 (2002-04-12)
In various cancers, inactivating mutations in the adenomatous polyposis coli or Axin tumor suppressor proteins or activating mutations in beta-catenin's amino-terminal domain elevate beta-catenin levels, resulting in marked effects on T-cell factor (TCF)-regulated transcription. Several candidate beta-catenin/TCF-regulated genes in cancer
Matrix metalloproteinases in the restorative proctocolectomy pouch of pediatric ulcerative colitis.
Makitalo, L; Piekkala, M; Ashorn, M; Pakarinen, M; Koivusalo, A; Karikoski, R; Natunen et al.
World Journal of Gastroenterology null
DSG3 facilitates cancer cell growth and invasion through the DSG3-plakoglobin-TCF/LEF-Myc/cyclin D1/MMP signaling pathway.
Chen, YJ; Lee, LY; Chao, YK; Chang, JT; Lu, YC; Li, HF; Chiu, CC; Li, YC; Li, YL; Chiou et al.
Testing null
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in HTLV-I-associated myelopathy.
Umehara, F, et al.
Journal of Neuropathology and Experimental Neurology, 57, 839-849 (1998)
Prognostic value of E-cadherin, beta-catenin, MMPs (7 and 9), and TIMPs (1 and 2) in patients with colorectal carcinoma.
Fernanda Roca, Laura V Mauro, Ana Morandi, Fernando Bonadeo, Carlos Vaccaro et al.
Journal of Surgical Oncology null
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