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MAB325

Sigma-Aldrich

Anti-Syntaxin Antibody, clone SP7

purified antibody, clone SP7, Chemicon®

Synonym(s):

Syntaxin 1A, Neuron-specific Antigen HPC-1, STX1A

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

antibody form

purified antibody

antibody product type

primary antibodies

clone

SP7, monoclonal

species reactivity

hamster, pig, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG2a

NCBI accession no.

NM_004603.2

UniProt accession no.

Q16623

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... STX1A(6804)

Specificity

Syntaxin (34-36 kDa). Reacts with syntaxin expressed in bacterial systems. Useful to investigators who transplant human neurons or human neural derived cell lines into rodents since the antibody reacts with human but poorly with rat syntaxin. Also useful in double labeling studies due to the fact it is an IgG2a subclass monoclonal.

Immunogen

Crude synaptic immunoprecipitate (human).

Application

Anti-Syntaxin Antibody, clone SP7 is an antibody against Syntaxin for use in ELISA, WB, IH.
Immunohistochemistry:1:10

Formalin fixed (fixed <4 weeks)

Immunoblotting: 1:10

ELISA: 1:10

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology

Physical form

Liquid

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB325:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Keisuke Okabe et al.
Cell, 159(3), 584-596 (2014-11-25)
Vascular and nervous systems, two major networks in mammalian bodies, show a high degree of anatomical parallelism and functional crosstalk. During development, neurons guide and attract blood vessels, and consequently this parallelism is established. Here, we identified a noncanonical neurovascular
W G Honer et al.
Brain research, 609(1-2), 9-20 (1993-04-23)
Synaptic pathology is likely to be an important feature of a number of neuropsychiatric illnesses. An antibody called EP10 was used previously to demonstrate a regional reduction in a 38 kDa synaptophysin-like protein in Alzheimer's disease. The SP antibodies were

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