FCMAB199P

Milli-Mark^® Anti-CD56-PE Antibody, clone C5.9

clone C5.9, Milli-Mark^®, from mouse

• Synonym(s): Neural cell adhesion molecule 1, NCAM-1
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

Properties

• biological source: mouse
• Quality Level: 100
• conjugate: PE
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: C5.9, monoclonal
• species reactivity: human
• manufacturer/tradename: Milli-Mark^®
• technique(s): flow cytometry: suitable
• isotype: IgG2bκ
• NCBI accession no.: NP_000606
• UniProt accession no.: P13591
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... NCAM1(4684)

Description

General description

CD56 is a membrane glycoprotein which has multiple isoforms generated by alternative splicing from a single gene located on chromosome 11 (Costa, 1997). The core polypeptide is the 140 kDa isoform which can be variably glycosylated to produce mature species. The predominant isoform in NK and T cells is the transmembrane-anchored 140 kDa protein. In tissues, CD56 antigen is found in the cerebellum and cortex of the brain, and at neuromuscular junctions. This molecule is identical to the 140 kDa isoform of the neuronal cell adhesion molecule (N-CAM) (Poggi, 2002; Lanier, 1989). Additionally, CD56 is also present in certain large granular lymphocyte leukemias, small cell lung carcinomas, neural-derived tumors, myelomas, and myeloid leukemias (Poggi, 2002).

Specificity

Antibody recognizes Human CD56 antigen.

Immunogen

Human NK Cells

Application

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

This Milli-Mark Anti-CD56-PE Antibody, clone C5.9 is validated for use in FC for the detection of CD56.

Quality

Evaluated by flow cytometry using human lymphocytes

Target description

140 kDa (Poggi, 2002; Lanier, 1989)

Physical form

Protein A purified

Purified Mouse monoclonal IgG2b conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Storage and Stability

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Analysis Note

Control
Human Lymphocytes

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable