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Safety Information

AG221

Sigma-Aldrich

Dopamine D2 Receptor Peptide

control for AB5084P, liquid

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.42

product name

Dopamine D2 Receptor, control peptide for AB5084P,

biological source

human

Quality Level

100

form

liquid

manufacturer/tradename

Chemicon®

concentration

1 mg/mL

technique(s)

cell based assay: suitable

NCBI accession no.

NM_000795.2
NM_016574.2

UniProt accession no.

P14416

shipped in

dry ice

General description

28 amino acid peptide sequence from the human D2 R within the cytoplasmic loop #3. The 28 amino acid sequence is shared by both the long and short form.

Application

For use in blocking the staining of AB5084P.

Optimal working dilution must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Physical form

Liquid in PBS, pH 7.5. No preservative.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

AG221:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hong Wang et al.
The Journal of comparative neurology, 442(4), 392-404 (2002-01-17)
Glutamatergic neurons within the deep layers of the prefrontal cortex and dopaminergic neurons of the substantia nigra pars compacta preferentially terminate in patch-like regions within the caudate putamen nucleus (CPN). Activation of dopamine D2 receptors is known to potently modulate
V A Boundy et al.
Molecular pharmacology, 43(5), 666-676 (1993-05-01)
Multiple subtypes of dopamine receptors with similar properties have been described. Ligands that have been shown to interact with a single subtype of receptor do not yet exist. The use of immunologic methods provides an alternative approach to distinguish receptors
F J Monsma et al.
Nature, 342(6252), 926-929 (1989-12-21)
Dopamine receptor belong to a large class of neurotransmitter and hormone receptors that are linked to their signal transduction pathways through guanine nucleotide binding regulatory proteins (G proteins). Pharmacological, biochemical and physiological criteria have been used to define two subcategories
Production and characterization of a monoclonal antibody to dopamine D2 receptor: comparison with a polyclonal antibody to a different epitope.
Farooqui, S M, et al.
Biochemical and biophysical research communications, 184, 661-667 (1992)
R Dal Toso et al.
The EMBO journal, 8(13), 4025-4034 (1989-12-20)
Cloned human dopamine D2 receptor cDNA was isolated from a pituitary cDNA library and found to encode an additional 29 amino acid residues in the predicted intracellular domain between transmembrane regions 5 and 6 relative to a previously described rat

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