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Key Documents

Safety Information

AB9016

Sigma-Aldrich

Anti-Chx10 Antibody, NT

Chemicon®, from sheep

Synonym(s):

Hox-10, Ocular Retardation, C. Elegans ceh-10 Homeo Domain Containing Homolog

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

sheep

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

bovine, human, rat, mouse

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

NM_182894.2

UniProt accession no.

P58304

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... VSX2(338917)

Specificity

Chx10

Immunogen

Epitope: N-terminus
Recombinant human Chx10 protein, N-terminal.

Application

Detect Chx10 using this Anti-Chx10 Antibody, N-terminus validated for use in WB.
Immunoblotting: 0.5-1.0 μg/mL. Reacts with the 46 kD protein in rat and mouse retinal tissue lysate.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

Neuronal & Glial Markers

Physical form

Format: Purified
Purified immunoglobulin. Liquid in PBS containing 0.08% sodium azide.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

AB9016:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sangbae Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(22), 10824-10833 (2019-05-11)
Rod and cone photoreceptors are light-sensing cells in the human retina. Rods are dominant in the peripheral retina, whereas cones are enriched in the macula, which is responsible for central vision and visual acuity. Macular degenerations affect vision the most
Ziming Luo et al.
Stem cells (Dayton, Ohio), 36(11), 1709-1722 (2018-07-13)
Effective derivation of three-dimensional (3D) retinal tissue from human-induced pluripotent stem cells (hiPSCs) could provide models for drug screening and facilitate patient-specific retinal cell replacement therapy. However, some hiPSC lines cannot undergo 3D self-organization and show inadequate differentiation efficiency to
Guilan Li et al.
Stem cells international, 2018, 4968658-4968658 (2018-07-17)
Urine cells, a body trash, have been successfully reprogrammed into human induced pluripotent stem cells (U-hiPSCs) which hold a huge promise in regenerative medicine. However, it is unknown whether or to what extent U-hiPSCs can generate retinal cells so far.
Noelia J Kunzevitzky et al.
Investigative ophthalmology & visual science, 51(7), 3800-3812 (2010-05-07)
PURPOSE. To describe how developing amacrine cells and retinal ganglion cells (RGCs) differ in survival signaling and global gene expression. METHODS. Amacrine cells were immunopurified and processed for gene microarray analysis. For survival studies, purified amacrine cells were cultured at
Harini V Gudiseva et al.
Genes, 12(12) (2021-12-25)
We intend to identify marker genes with differential gene expression (DEG) and RGC subtypes in cultures of human-induced pluripotent stem cell (iPSC)-derived retinal ganglion cells. Single-cell sequencing was performed on mature and functional iPSC-RGCs at day 40 using Chromium Single
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