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Key Documents

Safety Information

AB4344

Sigma-Aldrich

Anti-LYAR Antibody (Ly1 Antibody reactive clone)

from rabbit, purified by affinity chromatography

Synonym(s):

Cell growth-regulating nucleolar protein, Protein expressed in male leptotene and zygotene spermatocytes 264, MLZ-264

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

technique(s)

western blot: suitable

NCBI accession no.

NP_079557

UniProt accession no.

Q08288

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

mouse ... Lyar(17089)

General description

LYAR, also known as Ly1 antibody reactive clone, has been found to regulate the intracellular strength that is stimulated by both T and B cell antigen receptors. It is essential for immune tolerance and certain changes to its function could stimulate the development of autoreactivity. LYAR is important in the immunological synapse and functions to inhibit the T cell response. LYAR is highly expressed in indifferentiated embryonic stem cells and may be important in maintaining the stem cell identity.

Immunogen

GST-tagged recombinant protein corresponding to mouse LYAR.

Application

Anti-LYAR Antibody (Ly1 reactive clone) detects level of LYAR (Ly1 antibody reactive clone) & has been published & validated for use in WB.
Research Sub Category
Immunoglobulins & Immunology

Pluripotent & Early Differentiation

Quality

Evaluated by Western Blot in mouse embryonic stem cell lysate.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected LYAR in 10 µg of mouse embryonic stem cell lysate.

Target description

~48 kDa observed

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

AB4344:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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