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AB3570P

Sigma-Aldrich

Anti-Organic Anion Transporting Polypeptide 1 Antibody

Chemicon®, from rabbit

Synonym(s):

oatp1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

NCBI accession no.

NM_016354.3

UniProt accession no.

Q96BD0

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SLCO4A1(28231)

Specificity

Recognizes rat Organic Ion Transporter Polypetide 1 (OATP1). The immunogen shows no significant sequence homology with other OATs or other proteins

SPECIES REACTIVITIES: The immunogen sequence is unique to rat. Reactivity with other species has not been confirmed.

Immunogen

A 17 amino acid peptide sequence near amino acid 285 of rat OATP1 (Jacquemin et al. 1994; Kullak-Ublick et al. 1995).

Application

Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
This Anti-Organic Anion Transporting Polypeptide 1 Antibody is validated for use in ELISA, WB for the detection of Organic Anion Transporting Polypeptide 1.
Western blot: 1-10 μg/mL using ECL.



ELISA: 0.5-1 μg/mL using 1 μg/mL immunogen per well.

Optimal working dilutions must be determined by the end user.

Physical form

Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For antibodies with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

AB3570P:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kyunghee Yang et al.
Molecular pharmaceutics, 11(3), 766-775 (2014-01-15)
Breast cancer resistance protein (BCRP) and multidrug resistance-associated protein 2 (MRP2) are members of the ATP binding cassette (ABC) transporter family located in the canalicular membrane of hepatocytes that mediate biliary excretion of many drugs and endogenous compounds. BCRP and
G A Kullak-Ublick et al.
Gastroenterology, 109(4), 1274-1282 (1995-10-01)
Based on a recently cloned rat liver organic anion transporter, we attempted to clone the corresponding human liver organic anion transporting polypeptide. A human liver complementary DNA library was screened with a specific rat liver complementary DNA probe. The human

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