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Key Documents

Safety Information

AB3541

Sigma-Aldrich

Anti-Tet Repressor Antibody

Chemicon®, from rabbit

Synonym(s):

TetR

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

bacteria

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

UniProt accession no.

P0ACT4

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

Burkholderia spp. ... Tetr(69452453)

Specificity

Tet repressor. The tet repressor protein (TetR) regulates transcription of a family of tetracycline resistance determinates in Gram-negative bacteria. The Tet system is the most widely used regulatory system for conditional gene expression in eukaryotic cells. TetR can be used for that purpose in some organisms without further modifications. In mammals and in a large variety of organisms, however eukaryotic transcriptional activator or repressor domains are fused to TetR to turn it into an efficient regulator.

Immunogen

Tet repressor.

Application

Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
This Anti-Tet Repressor Antibody is validated for use in WB for the detection of Tet Repressor.
Western blot: 1:1,000. The detection limit is 0.8 ng.

Optimal working dilutions must be determined by the end user.

Physical form

Affinity purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

AB3541:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tracy J Berg et al.
The Journal of biological chemistry, 285(46), 35255-35266 (2010-08-17)
Ras and Rho small GTPases possessing a C-terminal polybasic region (PBR) are vital signaling proteins whose misregulation can lead to cancer. Signaling by these proteins depends on their ability to bind guanine nucleotides and their prenylation with a geranylgeranyl or

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