AB3478

Anti-Defensin β3 Antibody

Chemicon^®, from rabbit

• Synonym(s): BD-3, hBD-3
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): ELISA: suitable; western blot: suitable
• NCBI accession no.: NM_018661.3
• UniProt accession no.: P81534
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... DEFB103A(414325) , DEFB103B(414325)

Description

General description

Beta Defensin-3 is a novel 5 kDa nonhemolytic antimicrobial protein peptide which may be important in the innate epithelial defense of infections by various microorganisms seen in skin and lung (such as cystic fibrosis).

Specificity

Recognizes the 5-6 kDa human Defensin-3, beta protein.

Immunogen

A synthetic peptide consisting of amino acids 23-33 [GIINTLQKYYC] of the human beta-defensin-3 protein.

Application

Anti-Defensin Antibody, β3 is an antibody against Defensin for use in ELISA & WB.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Western blotting: Tricine-SDS- PAGE gels recommended: 1:500-1:1,000, migrates as a 5-6kDa band; Tricine-SDS-urea PAGE gels: Native Beta Defensin 3 migrates as a 9kDa band; the larger size is because of the reduction of the three cysteine bridges present in the peptide protein

Optimal working dilutions must be determined by the end user.

Physical form

Format: Purified

Purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable