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Key Documents

Safety Information

AB2218

Sigma-Aldrich

Anti-Aquaporin-4 Antibody

CHEMICON®, rabbit polyclonal

Synonym(s):

AQP4, WCH4, MIWC

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

product name

Anti-Aquaporin 4 Antibody, Chemicon®, from rabbit

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, mouse, rat

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

NM_001650.4
NM_004028.3

UniProt accession no.

P55087

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... AQP4(361)

General description

The water-specific channel Aquaporin 4 is located in various tissues including the gastro intestinal tract, kidney and brain. It is an osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. The localization of AQ4 to astrocyte endfeet makes it an excellent marker for astrocyte distal processes.

Specificity

Recognizes Aquaporin 4.
The antibody has not yet been tested for cross-reactivity to other species. The immunogen shows 94% similarity to mouse, 88% to bovine, 86% to rabbit and 82% to human AQP4 (hAQP4).

Immunogen

Epitope: C-Terminus
Synthetic Linear Peptide

Application

Anti-Aquaporin 4 Antibody is an antibody against Aquaporin 4 for use in WB.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
Western Blotting: 0.5-1 μg/mL using Chemiluminescence technique.

Optimal working dilutions must be determined by end user.

Target description

~34 kDa

Linkage

Replaces: AB3068

Physical form

ImmunoAffinity Purified
Purified in PBS with 0.05% NaN3

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Analysis Note

Control
Tested on adult rat brain lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

AB2218:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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