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Safety Information

AB15708A4

Sigma-Aldrich

Anti-Beta III Tubulin Antibody, Alexa Fluor™ 488 Conjugate | AB15708A4

from rabbit, ALEXA FLUOR™ 488

Synonym(s):

Tubulin beta-4, Tubulin beta-III, tubulin, beta 3, tubulin, beta, 4

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

ALEXA FLUOR™ 488

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, mouse

species reactivity (predicted by homology)

human (based on 100% sequence homology)

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable

NCBI accession no.

NP_006077

UniProt accession no.

Q13509

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... TUBB3(10381)
mouse ... Tubb3(22152)
rat ... Tubb3(246118)

General description

Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.

Specificity

This antibody recognizes Beta III Tubulin.

Immunogen

Synthetic linear peptide corresponding to human Beta III Tubulin.

Application

Immunohistochemistry: Representive lot has been shown to work in adult mouse brain.
Research Category
Neuroscience
Research Sub Category
Neurofilament & Neuron Metabolism

Quality

Evaluated by Immunocytochemistry in rat E18 cortex cells.

Immunocytochemistry Analysis: A 1:400 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells.

Target description

50 kDa calculated

Physical form

Affinity purified
Purified rabbit polyclonal conjugated to Alexa Fluor™ 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Rat E18 cortex cells

Legal Information

ALEXA FLUOR is a trademark of Life Technologies

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

AB15708A4:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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