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Key Documents

Safety Information

8.20610

Sigma-Aldrich

Glyoxal

(40% solution in water) for synthesis

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About This Item

UNSPSC Code:
12352114
NACRES:
NA.22

vapor pressure

20.2 hPa ( 20 °C)

Quality Level

autoignition temp.

285 °C

potency

2000-5000 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rat)

pH

2-3 (20 °C in H2O)

bp

104 °C/1013 hPa

mp

-14 °C

density

1.27 g/cm3 at 20 °C

storage temp.

2-30°C

Application


  • HFIP-Mediated Multicomponent Reactions: Research demonstrates the use of HFIP (Hexafluoroisopropanol) in synthesizing pyrazole-linked thiazole derivatives, highlighting a new application in organic synthesis. Glyoxal is instrumental in the development of these multifunctional structures, contributing to advanced material design (Banerjee et al., 2024).

  • Peptide Stapling in Protein Engineering: A study describes peptide stapling techniques using alpha-ketoaldehydes, which crosslink amines through glyoxal-modified linkers. This approach is pivotal in creating stable peptide structures for therapeutic applications (Guo et al., 2024).

Analysis Note

Assay (acidimetric): 39.0 - 41.0 %
Density (d 20 °C/ 4 °C): 1.266 - 1.271

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Muta. 2 - Skin Corr. 1 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 1


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names


Certificates of Analysis (COA)

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