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539573

Sigma-Aldrich

PKC Inhibitor Set

The PKC Inhibitor Set controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)
protect from light

solubility

DMSO: soluble

shipped in

ambient

storage temp.

−20°C

General description

Contains 250 µg of Bisindolylmaleimide I (Cat. No. 203290), 50 µg of Calphostin C, Cladosporium cladosporioides (Cat. No. 208725), 5 mg of Chelerythrine Chloride (Cat. No. 220285), 500 µg of Gö 6976 (Cat. No. 365250), 500 µg of Myristoylated Protein Kinase C Inhibitor 20-28, Cell-Permeable (Cat. No. 476480), and 1 mg of Ro-32-0432 (Cat. No. 557525). Supplied with a data sheet.
Inhibition of protein kinase C (PKC) is one of the most direct methods for investigating its role in cellular metabolism and tumorigenesis. Calbiochem® brand is pleased to offer a convenient set of PKC inhibitors for your research needs. Supplied with a data sheet.
The PKC Inhibitor Set controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Biochem/physiol Actions

Primary Target
PKC
Secondary Target
PKCα, PKCβ

Warning

Toxicity: Multiple Toxicity Values, refer to MSDS (O)

Reconstitution

Following reconstitution, aliquot and freeze -20°C.

Other Notes

Eicholtz, T., et al. 1993. J. Biol. Chem.268, 1982.
Kleinschroth, J., et al. 1993. Bioorg. Med. Chem. Lett.3, 1959.
Martiny-Baron, G.M., et al. 1993. J. Biol. Chem.268, 9194.
Ward, N.E., and O′Brian, C.A. 1993. Biochemistry32, 11903.
Wilkinson, S.E., et al. 1993. Biochem. J.294, 335.
Barg, J., et al. 1992. J. Neurochem.59, 1145.
Gopalakrishna, R., et al. 1992. FEBS Lett.314, 149.
Bruns, R.F., et al. 1991. Biochem. Biophys. Res. Commun.176, 288.
Toullec, D., et al. 1991. J. Biol. Chem.266, 15771.
Herbert, J.M., et al. 1990. Biochem. Biophys. Res. Commun.1172, 993.
Tamaoki, T., et al. 1990. Biotechnology8, 732.
Kobayashi, E., et al. 1989. Biochem. Biophys. Res. Commun.159, 548.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

539573-1SET:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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